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CRK6 cysteine-rich RLK (RECEPTOR-like protein kinase) 6 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828413, updated on 18-Sep-2024

Summary

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Official Symbol
CRK6
Official Full Name
cysteine-rich RLK (RECEPTOR-like protein kinase) 6
Primary source
TAIR:AT4G23140
Locus tag
AT4G23140
See related
Araport:AT4G23140
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
cysteine-rich RLK (RECEPTOR-like protein kinase) 6; F7H19.330; F7H19_330; RECEPTOR-LIKE PROTEIN KINASE
Summary
Arabidopsis thaliana receptor-like protein kinase. Naming convention from Chen et al 2003 (PMID 14756307)
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Genomic context

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See CRK6 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
7
Sequence:
Chromosome: 4; NC_003075.7 (12121369..12124564)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Bromo-adjacent homology (BAH) domain-containing protein Neighboring gene cysteine-rich RLK (RECEPTOR-like protein kinase) 5 Neighboring gene cysteine-rich RLK (RECEPTOR-like protein kinase) 7 Neighboring gene cysteine-rich RECEPTOR-like kinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Arabidopsis thaliana cysteine-rich receptor-like kinases CRK6 and CRK7 protect against apoplastic oxidative stress. Idänheimo N, et al. Biochem Biophys Res Commun, 2014 Mar 7. PMID 24530916
  2. Interaction of a protein phosphatase with an Arabidopsis serine-threonine receptor kinase. Stone JM, et al. Science, 1994 Nov 4. PMID 7973632
  3. Enhanced Arabidopsis pattern-triggered immunity by overexpression of cysteine-rich receptor-like kinases. Yeh YH, et al. Front Plant Sci, 2015. PMID 26029224, Free PMC Article
  4. Interaction of the maize and Arabidopsis kinase interaction domains with a subset of receptor-like protein kinases: implications for transmembrane signaling in plants. Braun DM, et al. Plant J, 1997 Jul. PMID 9263453
  5. Specific targeting of a plasmodesmal protein affecting cell-to-cell communication. Thomas CL, et al. PLoS Biol, 2008 Jan. PMID 18215111, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CRK6 and CRK7 are active protein kinases with differential preference for divalent cations. O3 sensitivity of crk6 and crk7 is disguised by redundancy effect.
    Title: The Arabidopsis thaliana cysteine-rich receptor-like kinases CRK6 and CRK7 protect against apoplastic oxidative stress.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_118443.3
NM_179095.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within response to reactive oxygen species IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
cysteine-rich RLK (RECEPTOR-like protein kinase) 6
NP_567678.1
  • cysteine-rich RLK (RECEPTOR-like protein kinase) 6 (CRK6); FUNCTIONS IN: kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: plasma membrane; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Protein of unknown function DUF26 (InterPro:IPR002902), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: cysteine-rich RLK (RECEPTOR-like protein kinase) 8 (TAIR:AT4G23160.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_849426.1
  • cysteine-rich RLK (RECEPTOR-like protein kinase) 6 (CRK6); FUNCTIONS IN: kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: plasma membrane; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Protein of unknown function DUF26 (InterPro:IPR002902), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: cysteine-rich RLK (RECEPTOR-like protein kinase) 8 (TAIR:AT4G23160.1); Has 119608 Blast hits to 118061 proteins in 4543 species: Archae - 108; Bacteria - 13357; Metazoa - 44377; Fungi - 10093; Plants - 34036; Viruses - 376; Other Eukaryotes - 17261 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    12121369..12124564
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118443.3 → NP_567678.1  cysteine-rich RLK (RECEPTOR-like protein kinase) 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567678.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O65466, Q8GX18, Q9C5S9
    UniProtKB/TrEMBL
    A0A654FRY8
    Conserved Domains (3) summary
    smart00219
    Location:356 → 613
    TyrKc; Tyrosine kinase, catalytic domain
    cd14066
    Location:357 → 623
    STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
    pfam01657
    Location:33 → 128
    Stress-antifung; Salt stress response/antifungal

  2. NM_179095.1 → NP_849426.1  cysteine-rich RLK (RECEPTOR-like protein kinase) 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849426.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A654FRY8
    Conserved Domains (3) summary
    smart00219
    Location:356 → 619
    TyrKc; Tyrosine kinase, catalytic domain
    cd14066
    Location:357 → 629
    STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
    pfam01657
    Location:33 → 128
    Stress-antifung; Salt stress response/antifungal
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9C5S9.1

Gene LinkOut

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