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CRF2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828475, updated on 22-Aug-2024

Summary

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Official Symbol
CRF2
Primary source
Araport:AT4G23750
Locus tag
AT4G23750
See related
TAIR:AT4G23750
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
cytokinin response factor 2; F9D16.220; F9D16_220; TARGET OF MONOPTEROS 3; TMO3
Summary
encodes a member of the ERF (ethylene response factor) subfamily B-5 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 7 members in this subfamily. Monopteros target gene.
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Genomic context

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See CRF2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
1
Sequence:
Chromosome: 4; NC_003075.7 (12376122..12378032)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Leucine-rich repeat protein kinase family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Cox19-like CHCH family protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CRF2 signaling is a novel regulator of cellular adhesion and migration in colorectal cancer cells. Ducarouge B, et al. PLoS One, 2013. PMID 24260200, Free PMC Article
  2. CYTOKININ RESPONSE FACTOR2 (CRF2) and CRF3 Regulate Lateral Root Development in Response to Cold Stress in Arabidopsis. Jeon J, et al. Plant Cell, 2016 Aug. PMID 27432872, Free PMC Article
  3. MONOPTEROS controls embryonic root initiation by regulating a mobile transcription factor. Schlereth A, et al. Nature, 2010 Apr 8. PMID 20220754
  4. A subset of Arabidopsis AP2 transcription factors mediates cytokinin responses in concert with a two-component pathway. Rashotte AM, et al. Proc Natl Acad Sci U S A, 2006 Jul 18. PMID 16832061, Free PMC Article
  5. CRFs form protein-protein interactions with each other and with members of the cytokinin signalling pathway in Arabidopsis via the CRF domain. Cutcliffe JW, et al. J Exp Bot, 2011 Oct. PMID 21705390, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_118506.3
NM_202870.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cotyledon development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within root development IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
cytokinin response factor 2
NP_194106.1
  • cytokinin response factor 2 (CRF2); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: cytokinin response factor 1 (TAIR:AT4G11140.1); Has 5899 Blast hits to 5717 proteins in 251 species: Archae - 0; Bacteria - 0; Metazoa - 6; Fungi - 2; Plants - 5881; Viruses - 0; Other Eukaryotes - 10 (source: NCBI BLink).
NP_974599.1
  • cytokinin response factor 2 (CRF2); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: cytokinin response factor 1 (TAIR:AT4G11140.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    12376122..12378032
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118506.3 → NP_194106.1  cytokinin response factor 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_194106.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8L701, Q9SUQ2
    UniProtKB/TrEMBL
    A0A178V319, A0A5S9XVL7
    Conserved Domains (1) summary
    smart00380
    Location:121 → 181
    AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs

  2. NM_202870.1 → NP_974599.1  cytokinin response factor 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_974599.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8L701, Q9SUQ2
    UniProtKB/TrEMBL
    A0A178V319, A0A5S9XVL7
    Conserved Domains (1) summary
    smart00380
    Location:121 → 181
    AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SUQ2.1

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