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BON2 Calcium-dependent phospholipid-binding Copine family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830621, updated on 18-Sep-2024

Summary

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Official Symbol
BON2
Official Full Name
Calcium-dependent phospholipid-binding Copine family protein
Primary source
TAIR:AT5G07300
Locus tag
AT5G07300
See related
Araport:AT5G07300
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
BONZAI 2; T2I1.10; T2I1_10
Summary
Encodes a copine-like protein, which is a member of a newly identified class of calcium-dependent, phospholipid binding proteins that are present in a wide range of organisms.
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Genomic context

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See BON2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
16
Sequence:
Chromosome: 5; NC_003076.8 (2299725..2303268)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene MEI2-like 4 Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene tRNA-Tyr

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Arabidopsis BAP1 and BAP2 genes are general inhibitors of programmed cell death. Yang H, et al. Plant Physiol, 2007 Sep. PMID 17631528, Free PMC Article
  2. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article
  3. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812
  4. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_120812.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables calcium-dependent phospholipid binding IEA
Inferred from Electronic Annotation
more info
  
enables calcium-dependent phospholipid binding NAS
Non-traceable Author Statement
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane HDA PubMed 
located_in plasmodesma HDA PubMed 

General protein information

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Preferred Names
Calcium-dependent phospholipid-binding Copine family protein
NP_568180.1
  • BONZAI 2 (BON2); FUNCTIONS IN: calcium-dependent phospholipid binding; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Copine (InterPro:IPR010734), C2 calcium-dependent membrane targeting (InterPro:IPR000008), von Willebrand factor, type A (InterPro:IPR002035); BEST Arabidopsis thaliana protein match is: DCD (Development and Cell Death) domain protein (TAIR:AT5G61910.4); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    2299725..2303268
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_120812.4 → NP_568180.1  Calcium-dependent phospholipid-binding Copine family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568180.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q5S1W2, Q94EW4, Q9LY30
    UniProtKB/TrEMBL
    A0A178UEP3, A0A5S9Y262
    Conserved Domains (3) summary
    cd04047
    Location:197 → 300
    C2B_Copine; C2 domain second repeat in Copine
    cd04048
    Location:47 → 164
    C2A_Copine; C2 domain first repeat in Copine
    cd01459
    Location:315 → 567
    vWA_copine_like; VWA Copine: Copines are phospholipid-binding proteins originally identified in paramecium. They are found in human and orthologues have been found in C. elegans and Arabidopsis Thaliana. None have been found in D. Melanogaster or S. Cereviciae. ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5S1W2.2

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