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Prp2 proline rich protein 2 [ Mus musculus (house mouse) ]

Gene ID: 83380, updated on 2-Nov-2024

Summary

Official Symbol
Prp2provided by MGI
Official Full Name
proline rich protein 2provided by MGI
Primary source
MGI:MGI:1932491
See related
Ensembl:ENSMUSG00000058295 AllianceGenome:MGI:1932491
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MP14
Summary
This gene encodes a member of the heterogeneous family of proline-rich salivary glycoproteins. The expression of this gene is dramatically induced in the parotid and submandibular glands of mice by beta-adrenergic stimulation. The encoded protein serves an important dental function by protecting mice against toxic dietary polyphenols such as tannins and influence the visco-elastic properties of the mucus. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 6. [provided by RefSeq, Nov 2015]
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Genomic context

See Prp2 in Genome Data Viewer
Location:
6 G1; 6 64.03 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (132572874..132577665)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (132595911..132600702)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 18326 Neighboring gene STARR-seq mESC enhancer starr_17509 Neighboring gene STARR-seq mESC enhancer starr_17510 Neighboring gene STARR-seq mESC enhancer starr_17511 Neighboring gene STARR-seq mESC enhancer starr_17512 Neighboring gene proline rich protein HaeIII subfamily 1 Neighboring gene RIKEN cDNA A630073D07 gene Neighboring gene taste receptor, type 2, member 120

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
proline-rich protein 2
Names
proline-rich protein MP-3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031499.3NP_113687.2  proline-rich protein 2 precursor

    See identical proteins and their annotated locations for NP_113687.2

    Status: REVIEWED

    Source sequence(s)
    AC124523
    Consensus CDS
    CCDS51931.1
    UniProtKB/TrEMBL
    F8VPU9
    Related
    ENSMUSP00000075435.4, ENSMUST00000076061.4

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    132572874..132577665
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)