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Disease resistance protein (TIR-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834157, updated on 18-Sep-2024

Summary

Official Full Name
Disease resistance protein (TIR-NBS-LRR class) family
Primary source
TAIR:AT5G41550
Locus tag
AT5G41550
See related
Araport:AT5G41550
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
MBK23.7; MBK23_7
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Genomic context

Location:
chromosome: 5
Exon count:
4
Sequence:
Chromosome: 5; NC_003076.8 (16617232..16620824, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Disease resistance protein (TIR-NBS-LRR class) family Neighboring gene DET1 complexing ubiquitin ligase Neighboring gene WRKY DNA-binding protein 24

General gene information

NM_123519.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ADP binding IEA
Inferred from Electronic Annotation
more info
 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
Disease resistance protein (TIR-NBS-LRR class) family
NP_198970.1
  • Disease resistance protein (TIR-NBS-LRR class) family; FUNCTIONS IN: transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: signal transduction, defense response, apoptosis, innate immune response; LOCATED IN: intrinsic to membrane; EXPRESSED IN: root; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (TIR-NBS-LRR class) family (TAIR:AT5G41750.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    16617232..16620824 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_123519.2NP_198970.1  Disease resistance protein (TIR-NBS-LRR class) family [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_198970.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UHM7, Q9FFS5
    Conserved Domains (6) summary
    cd00009
    Location:212327
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    COG4886
    Location:628787
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00033
    Location:607629
    LRR_RI; leucine-rich repeat [structural motif]
    pfam00931
    Location:189443
    NB-ARC; NB-ARC domain
    pfam01582
    Location:13175
    TIR; TIR domain
    pfam07725
    Location:607625
    LRR_3; Leucine Rich Repeat