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TIP2;3 tonoplast intrinsic protein 2;3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 834794, updated on 18-Sep-2024

Summary

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Official Symbol
TIP2;3
Official Full Name
tonoplast intrinsic protein 2;3
Primary source
TAIR:AT5G47450
Locus tag
AT5G47450
See related
Araport:AT5G47450
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA TONOPLAST INTRINSIC PROTEIN 2;3; ATTIP2;3; DELTA-TIP3; DELTA-TONOPLAST INTRINSIC PROTEIN 3; MNJ7.4; MNJ7_4; tonoplast intrinsic protein 2;3
Summary
Tonoplast intrinsic protein, transports ammonium (NH3) and methylammonium across the tonoplast membrane, gene expression shows diurnal regulation and is upregulated by ammonium (NH3).
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Genomic context

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See TIP2;3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
2
Sequence:
Chromosome: 5; NC_003076.8 (19248249..19249622, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene formyltetrahydrofolate deformylase Neighboring gene auxin canalization protein (DUF828) Neighboring gene pseudo Neighboring gene miscRNA Neighboring gene uncharacterized protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Tonoplast intrinsic proteins AtTIP2;1 and AtTIP2;3 facilitate NH3 transport into the vacuole. Loqué D, et al. Plant Physiol, 2005 Feb. PMID 15665250, Free PMC Article
  2. In vivo imaging of the tonoplast intrinsic protein family in Arabidopsis roots. Gattolin S, et al. BMC Plant Biol, 2009 Nov 18. PMID 19922653, Free PMC Article
  3. The Arabidopsis abiotic stress-induced TSPO-related protein reduces cell-surface expression of the aquaporin PIP2;7 through protein-protein interactions and autophagic degradation. Hachez C, et al. Plant Cell, 2014 Dec. PMID 25538184, Free PMC Article
  4. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
  5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_124117.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ammonium channel activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables channel activity IEA
Inferred from Electronic Annotation
more info
  
enables methylammonium transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables water channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in central vacuole IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plant-type vacuole membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
tonoplast intrinsic protein 2;3
NP_199556.1
  • tonoplast intrinsic protein 2;3 (TIP2;3); CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: tonoplast intrinsic protein 2;2 (TAIR:AT4G17340.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    19248249..19249622 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_124117.3 → NP_199556.1  tonoplast intrinsic protein 2;3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_199556.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0WNU5, Q53XE4, Q9FGL2
    UniProtKB/TrEMBL
    A0A178UJ23, A0A5S9YC53, A0A654G9D2
    Conserved Domains (1) summary
    PLN00166
    Location:1 → 250
    PLN00166; aquaporin TIP2; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9FGL2.1

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