U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Dedd death effector domain-containing [ Rattus norvegicus (Norway rat) ]

Gene ID: 83631, updated on 2-Nov-2024

Summary

Official Symbol
Deddprovided by RGD
Official Full Name
death effector domain-containingprovided by RGD
Primary source
RGD:620050
See related
EnsemblRapid:ENSRNOG00000003779 AllianceGenome:RGD:620050
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Deft
Summary
Predicted to enable DNA binding activity. Involved in spermatogenesis. Predicted to be located in cytoplasm. Predicted to be active in nucleolus. Orthologous to human DEDD (death effector domain containing). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 123.9), Muscle (RPKM 106.0) and 9 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Dedd in Genome Data Viewer
Location:
13q24
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (86286341..86301789)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (83755874..83769982)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (89706932..89721825)

Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 21 Neighboring gene ubiquitin-fold modifier conjugating enzyme 1 Neighboring gene G protein subunit gamma 5, pseudogene 1 Neighboring gene nitrilase 1 Neighboring gene prefoldin subunit 2 Neighboring gene kelch domain containing 9

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
death effector domain-containing protein
Names
death effector domain-containing testicular molecule

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031800.1NP_113988.1  death effector domain-containing protein

    See identical proteins and their annotated locations for NP_113988.1

    Status: PROVISIONAL

    Source sequence(s)
    AF053362
    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086031.1 Reference GRCr8

    Range
    86286341..86301789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017598942.3XP_017454431.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD
  2. XM_017598945.3XP_017454434.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD
  3. XM_017598943.3XP_017454432.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
    Related
    ENSRNOP00000005147.1, ENSRNOT00000005147.4
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD
  4. XM_006250269.5XP_006250331.1  death effector domain-containing protein isoform X1

    See identical proteins and their annotated locations for XP_006250331.1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD
  5. XM_063272644.1XP_063128714.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
  6. XM_063272646.1XP_063128716.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
  7. XM_006250274.5XP_006250336.1  death effector domain-containing protein isoform X1

    See identical proteins and their annotated locations for XP_006250336.1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD
  8. XM_039091125.2XP_038947053.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD
  9. XM_006250272.5XP_006250334.1  death effector domain-containing protein isoform X1

    See identical proteins and their annotated locations for XP_006250334.1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD
  10. XM_017598946.3XP_017454435.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD
  11. XM_017598944.3XP_017454433.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD
  12. XM_063272648.1XP_063128718.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
  13. XM_063272647.1XP_063128717.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
  14. XM_063272650.1XP_063128720.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
  15. XM_063272649.1XP_063128719.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
  16. XM_063272645.1XP_063128715.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6
  17. XM_063272643.1XP_063128713.1  death effector domain-containing protein isoform X1

    UniProtKB/Swiss-Prot
    Q9Z2K0
    UniProtKB/TrEMBL
    A6JFX6