RAC10 RAC-like 10 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: RAC10
Official Full Name: RAC-like 10
Primary source: TAIR:AT5G62880
Locus tag: AT5G62880
See related: Araport:AT5G62880
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA RAC-LIKE 10; ARAC10; ATRAC10; ATROP11; MQB2.180; MQB2_180; RAC-like 10; RHO-related protein from plants 11; RHO-RELATED PROTEIN FROM PLANTS 11; ROP11
Summary: A member of ROP GTPase gene family.
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Genomic context

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See RAC10 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 8

Sequence:: Chromosome: 5; NC_003076.8 (25236945..25239262)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The model predicted that a positive feedback and slow diffusion of ROP11-ROPGEF4 complex were required to generate ROP-activated plasma membrane domains.
Title: A Rho-based reaction-diffusion system governs cell wall patterning in metaxylem vessels.
Data indicate that ROP11 GTPase (At5g62880) can be activated locally at the plasma membrane.
Title: A Rho-actin signaling pathway shapes cell wall boundaries in Arabidopsis xylem vessels.
ROP11 protects ABI1 phosphatase activity from inhibition by RCAR1/PYL9 and thus negatively regulates abscissic acid signaling.[ROP11]
Title: ROP11 GTPase negatively regulates ABA signaling by protecting ABI1 phosphatase activity from inhibition by the ABA receptor RCAR1/PYL9 in Arabidopsis.
ROP11 is a negative regulator of multiple abscissic acid responses in Arabidopsis.[ROP11]
Title: ROP11 GTPase is a negative regulator of multiple ABA responses in Arabidopsis.
ROPGEF1 and ROPGEF4 are specific regulators of ROP11 function in ABA-mediated stomatal closure. [ROP11]
Title: ROPGEF1 and ROPGEF4 are functional regulators of ROP11 GTPase in ABA-mediated stomatal closure in Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_125682.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables GTP binding	TAS Traceable Author Statement more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein phosphatase binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of abscisic acid-activated signaling pathway	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within plant-type cell wall organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of plant-type cell wall cellulose biosynthetic process	IGI Inferred from Genetic Interaction more info	PubMed
involved_in small GTPase-mediated signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	ISM Inferred from Sequence Model more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in secondary cell wall	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: RAC-like 10

NP_201093.1

RAC-like 10 (RAC10); FUNCTIONS IN: GTP binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Ras small GTPase, Rab type (InterPro:IPR003579), Ras (InterPro:IPR013753), Ras small GTPase, Ras type (InterPro:IPR003577), Small GTPase, Rho type (InterPro:IPR003578); BEST Arabidopsis thaliana protein match is: RHO-related protein from plants 10 (TAIR:AT3G48040.1); Has 24116 Blast hits to 24088 proteins in 664 species: Archae - 8; Bacteria - 52; Metazoa - 12643; Fungi - 3430; Plants - 2696; Viruses - 20; Other Eukaryotes - 5267 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003076.8 Reference assembly

Range

25236945..25239262

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001345564.1 → NP_001331034.1 RAC-like 10 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8BCM4, A0A654FEQ4

Conserved Domains (1) summary

cd04133
Location:8 → 166

Rop_like; Rho-related protein from plants (Rop)-like
NM_125682.5 → NP_201093.1 RAC-like 10 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_201093.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O82481

UniProtKB/TrEMBL

A0A178UC00, A0A384LM06, Q67XC6, Q683A3

Conserved Domains (1) summary

cd04133
Location:8 → 180

Rop_like; Rho-related protein from plants (Rop)-like