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XRCC2 homolog of X-ray repair cross complementing 2 (XRCC2) [ Arabidopsis thaliana (thale cress) ]

Gene ID: 836573, updated on 18-Sep-2024

Summary

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Official Symbol
XRCC2
Official Full Name
homolog of X-ray repair cross complementing 2 (XRCC2)
Primary source
TAIR:AT5G64520
Locus tag
AT5G64520
See related
Araport:AT5G64520
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATXRCC2; homolog of X-ray repair cross complementing 2; homolog of X-ray repair cross complementing 2 (XRCC2); MUB3.4; MUB3_4
Summary
Encodes a protein of the XRCC2 family involved in DNA repair. atxrcc2-1 Mutants are sensitive to MitomycinC but do not show fertility defects.
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Genomic context

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See XRCC2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
8
Sequence:
Chromosome: 5; NC_003076.8 (25787969..25791197)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene tunicamycin induced protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene xylem NAC domain 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Effects of XRCC2 and RAD51B mutations on somatic and meiotic recombination in Arabidopsis thaliana. Da Ines O, et al. Plant J, 2013 Jun. PMID 23521529
  2. The Arabidopsis homologue of Xrcc3 plays an essential role in meiosis. Bleuyard JY, et al. EMBO J, 2004 Jan 28. PMID 14726957, Free PMC Article
  3. Roles of XRCC2, RAD51B and RAD51D in RAD51-independent SSA recombination. Serra H, et al. PLoS Genet, 2013 Nov. PMID 24278037, Free PMC Article
  4. Differing requirements for the Arabidopsis Rad51 paralogs in meiosis and DNA repair. Bleuyard JY, et al. Plant J, 2005 Feb. PMID 15686518
  5. Identification and dynamics of Arabidopsis adaptor protein-2 complex and its involvement in floral organ development. Yamaoka S, et al. Plant Cell, 2013 Aug. PMID 23975897, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001345633.1
NM_001345634.1
NM_001345635.1
NM_001345637.1
NM_001345638.1
NM_001345639.1
NM_001345640.1
NM_001345641.1
NM_125848.3
NM_180937.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP-dependent DNA damage sensor activity IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within double-strand break repair via homologous recombination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within reciprocal meiotic recombination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of Rad51B-Rad51C-Rad51D-XRCC2 complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in replication fork IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
homolog of X-ray repair cross complementing 2 (XRCC2)
NP_001318876.1
  • homolog of X-ray repair cross complementing 2 (XRCC2) (XRCC2); Has 186 Blast hits to 186 proteins in 75 species: Archae - 0; Bacteria - 0; Metazoa - 99; Fungi - 44; Plants - 31; Viruses - 0; Other Eukaryotes - 12 (source: NCBI BLink).
NP_201257.2
  • homolog of X-ray repair cross complementing 2 (XRCC2) (XRCC2); Has 215 Blast hits to 213 proteins in 83 species: Archae - 0; Bacteria - 0; Metazoa - 115; Fungi - 49; Plants - 37; Viruses - 0; Other Eukaryotes - 14 (source: NCBI BLink).
NP_851268.1
  • homolog of X-ray repair cross complementing 2 (XRCC2) (XRCC2); Has 216 Blast hits to 214 proteins in 83 species: Archae - 0; Bacteria - 0; Metazoa - 116; Fungi - 49; Plants - 37; Viruses - 0; Other Eukaryotes - 14 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    25787969..25791197
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001345636.1 → NP_001330643.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBH3, A0A5S9YGX0
    Conserved Domains (1) summary
    cd19490
    Location:43 → 305
    XRCC2; XRCC2 recombinase

  2. NM_180937.2 → NP_851268.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_851268.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q682D3, Q8GVF2, Q9FLG6
    UniProtKB/TrEMBL
    A0A178UIJ5, A0A5S9YGX0
    Conserved Domains (1) summary
    cd19490
    Location:43 → 299
    XRCC2; XRCC2 recombinase

  3. NM_001345637.1 → NP_001330642.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBF2, A0A5S9YGX0, A0A7G2FJR3
    Conserved Domains (1) summary
    cd19490
    Location:43 → 299
    XRCC2; XRCC2 recombinase

  4. NM_125848.3 → NP_201257.2  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_201257.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UKI8, A0A5S9YGX0, F4KDQ6
    Conserved Domains (1) summary
    cd19490
    Location:43 → 299
    XRCC2; XRCC2 recombinase

  5. NM_001345638.1 → NP_001330647.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UJL6, A0A1P8BBG3, A0A384LLW8, A0A5S9YGX0

  6. NM_001345639.1 → NP_001330646.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBI8

  7. NM_001345640.1 → NP_001330649.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBG6

  8. NM_001345641.1 → NP_001330644.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBF9, A0A5S9YGX0, A0A7G2FKH2
    Conserved Domains (1) summary
    cd19490
    Location:43 → 305
    XRCC2; XRCC2 recombinase

  9. NM_001345633.1 → NP_001330648.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBG4, A0A5S9YGX0

  10. NM_001345635.1 → NP_001318876.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2H1ZE99, A0A5S9YGX0
    Conserved Domains (1) summary
    cd19490
    Location:43 → 305
    XRCC2; XRCC2 recombinase

  11. NM_001345634.1 → NP_001330645.1  homolog of X-ray repair cross complementing 2 (XRCC2) [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BBF0
    Conserved Domains (1) summary
    cd19490
    Location:43 → 299
    XRCC2; XRCC2 recombinase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q682D3.2

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