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DPE1 disproportionating enzyme [ Arabidopsis thaliana (thale cress) ]

Gene ID: 836609, updated on 18-Sep-2024

Summary

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Official Symbol
DPE1
Official Full Name
disproportionating enzyme
Primary source
TAIR:AT5G64860
Locus tag
AT5G64860
See related
Araport:AT5G64860
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
disproportionating enzyme; MXK3.9; MXK3_9
Summary
Encodes a maltotriose-metabolizing enzyme with chloroplastic alpha-1,4-glucanotransferase activity. Mutant has altered starch degradation.
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Genomic context

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See DPE1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
16
Sequence:
Chromosome: 5; NC_003076.8 (25925173..25928879, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene tRNA-Leu Neighboring gene SPFH/Band 7/PHB domain-containing membrane-associated protein family Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Disproportionating Enzyme 1 (DPE1). O'Neill EC, et al. J Biol Chem, 2015 Dec 11. PMID 26504082, Free PMC Article
  2. Blocking the metabolism of starch breakdown products in Arabidopsis leaves triggers chloroplast degradation. Stettler M, et al. Mol Plant, 2009 Nov. PMID 19946617, Free PMC Article
  3. A critical role for disproportionating enzyme in starch breakdown is revealed by a knock-out mutation in Arabidopsis. Critchley JH, et al. Plant J, 2001 Apr. PMID 11359613
  4. Mutations in leaf starch metabolism modulate the diurnal root growth profiles of Arabidopsis thaliana. Yazdanbakhsh N, et al. Plant Signal Behav, 2011 Jul. PMID 21691153, Free PMC Article
  5. Starch degradation. Smith AM, et al. Annu Rev Plant Biol, 2005. PMID 15862090

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. AtDPE1 forms a homodimer with a deep, long, and open-ended active site canyon contained within each subunit
    Title: Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Disproportionating Enzyme 1 (DPE1).
  2. pgm, sex1, mex1, dpe1 and dpe2 starch metabolism mutants grown in three different photoperiods display root growth patterns of all genotypes characteristic modifications in their diurnal kinetics that were also affected by the photoperiod.
    Title: Mutations in leaf starch metabolism modulate the diurnal root growth profiles of Arabidopsis thaliana.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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NM_125884.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 4-alpha-glucanotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables 4-alpha-glucanotransferase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within glucose metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in maltose catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within starch catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in starch catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within starch catabolic process TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
disproportionating enzyme
NP_201291.1
  • disproportionating enzyme (DPE1); FUNCTIONS IN: 4-alpha-glucanotransferase activity, cation binding, catalytic activity; INVOLVED IN: response to cold, starch catabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glycoside hydrolase, family 77 (InterPro:IPR003385), Glycoside hydrolase, catalytic core (InterPro:IPR017853), Glycoside hydrolase, subgroup, catalytic core (InterPro:IPR013781); BEST Arabidopsis thaliana protein match is: disproportionating enzyme 2 (TAIR:AT2G40840.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    25925173..25928879 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_125884.4 → NP_201291.1  disproportionating enzyme [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_201291.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LV91
    UniProtKB/TrEMBL
    A0A178U766, A0A5S9YH17, A0A654GE62
    Conserved Domains (1) summary
    PLN02635
    Location:56 → 576
    PLN02635; disproportionating enzyme
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LV91.1

Gene LinkOut

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