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APK4 adenosine-5'-phosphosulfate (APS) kinase 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 836888, updated on 18-Sep-2024

Summary

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Official Symbol
APK4
Official Full Name
adenosine-5'-phosphosulfate (APS) kinase 4
Primary source
TAIR:AT5G67520
Locus tag
AT5G67520
See related
Araport:AT5G67520
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
adenosine-5'-phosphosulfate (APS) kinase 4; K9I9.8; K9I9_8
Summary
Provides activated sulfate for the sulfation of secondary metabolites, including the glucosinolates. Redundant with APK3.
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Genomic context

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See APK4 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
6
Sequence:
Chromosome: 5; NC_003076.8 (26939159..26941050)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene succinate dehydrogenase assembly factor Neighboring gene voltage dependent anion channel 2 Neighboring gene Translation protein SH3-like family protein Neighboring gene plant U-box 49 Neighboring gene Arabinanase/levansucrase/invertase Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Adenosine-5'-phosphosulfate kinase is essential for Arabidopsis viability. Mugford SG, et al. FEBS Lett, 2010 Jan 4. PMID 19903478
  2. Disruption of adenosine-5'-phosphosulfate kinase in Arabidopsis reduces levels of sulfated secondary metabolites. Mugford SG, et al. Plant Cell, 2009 Mar. PMID 19304933, Free PMC Article
  3. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
  4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001345834.1
NM_001345835.1
NM_126152.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables adenylylsulfate kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables adenylylsulfate kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in hydrogen sulfide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within male gamete generation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in sulfate assimilation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plastid TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
adenosine-5'-phosphosulfate (APS) kinase 4
NP_569050.1
  • adenosine-5'-phosphosulfate (APS) kinase 4 (APK4); FUNCTIONS IN: kinase activity, transferase activity, transferring phosphorus-containing groups, ATP binding; INVOLVED IN: male gamete generation, sulfate assimilation; LOCATED IN: chloroplast, plastid; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Adenylylsulphate kinase, C-terminal (InterPro:IPR002891); BEST Arabidopsis thaliana protein match is: APS kinase (TAIR:AT2G14750.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    26939159..26941050
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_126152.5 → NP_569050.1  adenosine-5'-phosphosulfate (APS) kinase 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_569050.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q84JF0, Q8LF64, Q9FJX1
    UniProtKB/TrEMBL
    A0A178UDQ3, A0A5S9YID9, A0A654GEX9, A0A7G2FND1
    Conserved Domains (1) summary
    cl17190
    Location:88 → 262
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  2. NM_001345834.1 → NP_001331607.1  adenosine-5'-phosphosulfate (APS) kinase 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BEE5

  3. NM_001345835.1 → NP_001331608.1  adenosine-5'-phosphosulfate (APS) kinase 4 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8BEE5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q84JF0.1

Gene LinkOut

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