U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CXXS1 C-terminal cysteine residue is changed to a serine 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837696, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
CXXS1
Official Full Name
C-terminal cysteine residue is changed to a serine 1
Primary source
TAIR:AT1G11530
Locus tag
AT1G11530
See related
Araport:AT1G11530
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATCXXS1; C-terminal cysteine residue is changed to a serine 1
Summary
Encodes a monocysteinic thioredoxin, thioredoxin in which the second cysteine of the redox site is replaced by a serine, with low disulfide reductase but efficient disulfide isomerase activity.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CXXS1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
3
Sequence:
Chromosome: 1; NC_003070.9 (3874396..3875484)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene DNA-binding storekeeper protein-related transcriptional regulator Neighboring gene pliceosome associated protein-like protein Neighboring gene ncRNA Neighboring gene Sulfite exporter TauE/SafE family protein Neighboring gene xyloglucan endotransglucosylase/hydrolase 8 Neighboring gene tRNA-Leu

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. AtCXXS: atypical members of the Arabidopsis thaliana thioredoxin h family with a remarkably high disulfide isomerase activity. Serrato AJ, et al. Physiol Plant, 2008 Jul. PMID 18384502
  2. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
  3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

NM_101026.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein disulfide isomerase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
NOT involved_in protein deglutathionylation IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region HDA PubMed 

General protein information

Go to the top of the page Help
Preferred Names
C-terminal cysteine residue is changed to a serine 1
NP_172620.1
  • C-terminal cysteine residue is changed to a serine 1 (CXXS1); CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin, core (InterPro:IPR015467), Thioredoxin-like (InterPro:IPR017936), Thioredoxin domain (InterPro:IPR013766), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: thioredoxin H-type 1 (TAIR:AT3G51030.1); Has 9365 Blast hits to 9347 proteins in 2322 species: Archae - 165; Bacteria - 5071; Metazoa - 947; Fungi - 584; Plants - 1098; Viruses - 0; Other Eukaryotes - 1500 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    3874396..3875484
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101026.3 → NP_172620.1  C-terminal cysteine residue is changed to a serine 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172620.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q2HIL3, Q8LDI5, Q9SYX9, Q9XH49
    UniProtKB/TrEMBL
    A0A178WIW7, A0A5S9TVM1
    Conserved Domains (1) summary
    cd02947
    Location:11 → 106
    TRX_family; TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8LDI5.2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools