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GAPA-2 glyceraldehyde 3-phosphate dehydrogenase A subunit 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837848, updated on 18-Sep-2024

Summary

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Official Symbol
GAPA-2
Official Full Name
glyceraldehyde 3-phosphate dehydrogenase A subunit 2
Primary source
TAIR:AT1G12900
Locus tag
AT1G12900
See related
Araport:AT1G12900
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F13K23.15; F13K23_15; glyceraldehyde 3-phosphate dehydrogenase A subunit 2
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Genomic context

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See GAPA-2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
5
Sequence:
Chromosome: 1; NC_003070.9 (4392438..4394454, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene nudix hydrolase homolog 12 Neighboring gene ncRNA Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene eukaryotic release factor 1-2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of multiple salicylic acid-binding proteins using two high throughput screens. Manohar M, et al. Front Plant Sci, 2014. PMID 25628632, Free PMC Article
  2. Regulation of Active DNA Demethylation by a Methyl-CpG-Binding Domain Protein in Arabidopsis thaliana. Li Q, et al. PLoS Genet, 2015 May. PMID 25933434, Free PMC Article
  3. Redox Conformation-Specific Protein-Protein Interactions of the 2-Cysteine Peroxiredoxin in Arabidopsis. Liebthal M, et al. Antioxidants (Basel), 2020 Jun 11. PMID 32545358, Free PMC Article
  4. Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana. Ferro M, et al. Mol Cell Proteomics, 2003 May. PMID 12766230
  5. Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study. Bindschedler LV, et al. Phytochemistry, 2008 Jul. PMID 18538804

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

NM_001084060.1
NM_001123804.1
NM_001198048.1
NM_101161.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables NADP binding IEA
Inferred from Electronic Annotation
more info
  
enables glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
  
enables salicylic acid binding HDA PubMed 
Process Evidence Code Pubs
involved_in glucose metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in reductive pentose-phosphate cycle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in apoplast HDA PubMed 
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast envelope HDA PubMed 
located_in chloroplast stroma HDA PubMed 
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in extracellular region HDA PubMed 

General protein information

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Preferred Names
glyceraldehyde 3-phosphate dehydrogenase A subunit 2
NP_001077529.1
  • glyceraldehyde 3-phosphate dehydrogenase A subunit 2 (GAPA-2); FUNCTIONS IN: glyceraldehyde-3-phosphate dehydrogenase activity; INVOLVED IN: glycolysis; LOCATED IN: apoplast, chloroplast, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (InterPro:IPR020829), Glyceraldehyde 3-phosphate dehydrogenase subfamily (InterPro:IPR000173), Glyceraldehyde 3-phosphate dehydrogenase family (InterPro:IPR020831), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, subgroup (InterPro:IPR020832), Glyceraldehyde 3-phosphate dehydrogenase, active site (InterPro:IPR020830), Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (InterPro:IPR020828); BEST Arabidopsis thaliana protein match is: glyceraldehyde 3-phosphate dehydrogenase A subunit (TAIR:AT3G26650.1); Has 24213 Blast hits to 24212 proteins in 6137 species: Archae - 36; Bacteria - 10763; Metazoa - 2201; Fungi - 2756; Plants - 3727; Viruses - 0; Other Eukaryotes - 4730 (source: NCBI BLink).
NP_001117276.1
  • glyceraldehyde 3-phosphate dehydrogenase A subunit 2 (GAPA-2); FUNCTIONS IN: NAD or NADH binding, glyceraldehyde-3-phosphate dehydrogenase activity; INVOLVED IN: oxidation reduction, glycolysis, glucose metabolic process; LOCATED IN: apoplast, chloroplast, membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Glyceraldehyde 3-phosphate dehydrogenase subfamily (InterPro:IPR000173), Glyceraldehyde 3-phosphate dehydrogenase family (InterPro:IPR020831), Glyceraldehyde-3-phosphate dehydrogenase, type I (InterPro:IPR006424), Glyceraldehyde 3-phosphate dehydrogenase, active site (InterPro:IPR020830), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (InterPro:IPR020829), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, subgroup (InterPro:IPR020832), Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (InterPro:IPR020828); BEST Arabidopsis thaliana protein match is: glyceraldehyde 3-phosphate dehydrogenase A subunit (TAIR:AT3G26650.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_001184977.1
  • glyceraldehyde 3-phosphate dehydrogenase A subunit 2 (GAPA-2); FUNCTIONS IN: NAD or NADH binding, glyceraldehyde-3-phosphate dehydrogenase activity; INVOLVED IN: oxidation reduction, glycolysis, glucose metabolic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glyceraldehyde 3-phosphate dehydrogenase subfamily (InterPro:IPR000173), Glyceraldehyde 3-phosphate dehydrogenase family (InterPro:IPR020831), Glyceraldehyde-3-phosphate dehydrogenase, type I (InterPro:IPR006424), Glyceraldehyde 3-phosphate dehydrogenase, active site (InterPro:IPR020830), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (InterPro:IPR020829), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, subgroup (InterPro:IPR020832), Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (InterPro:IPR020828); BEST Arabidopsis thaliana protein match is: glyceraldehyde 3-phosphate dehydrogenase A subunit (TAIR:AT3G26650.1).
NP_172750.1
  • glyceraldehyde 3-phosphate dehydrogenase A subunit 2 (GAPA-2); FUNCTIONS IN: NAD or NADH binding, glyceraldehyde-3-phosphate dehydrogenase activity; INVOLVED IN: oxidation reduction, glycolysis, glucose metabolic process; LOCATED IN: apoplast, chloroplast stroma, chloroplast, membrane, chloroplast envelope; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Glyceraldehyde 3-phosphate dehydrogenase subfamily (InterPro:IPR000173), Glyceraldehyde 3-phosphate dehydrogenase family (InterPro:IPR020831), Glyceraldehyde-3-phosphate dehydrogenase, type I (InterPro:IPR006424), Glyceraldehyde 3-phosphate dehydrogenase, active site (InterPro:IPR020830), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (InterPro:IPR020829), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, subgroup (InterPro:IPR020832), Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (InterPro:IPR020828); BEST Arabidopsis thaliana protein match is: glyceraldehyde 3-phosphate dehydrogenase A subunit (TAIR:AT3G26650.1); Has 24704 Blast hits to 24695 proteins in 6149 species: Archae - 47; Bacteria - 10700; Metazoa - 2230; Fungi - 2778; Plants - 3753; Viruses - 0; Other Eukaryotes - 5196 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    4392438..4394454 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001332055.1 → NP_001321059.1  glyceraldehyde 3-phosphate dehydrogenase A subunit 2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8APR6, A0A7G2ET00
    Conserved Domains (1) summary
    PLN03096
    Location:48 → 441
    PLN03096; glyceraldehyde-3-phosphate dehydrogenase A; Provisional

  2. NM_101161.3 → NP_172750.1  glyceraldehyde 3-phosphate dehydrogenase A subunit 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172750.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B3H4P2, C0Z2Y9, Q9LPW0
    UniProtKB/TrEMBL
    A0A178WA64, A0A5S9U5M4, A0A7G2ET00
    Conserved Domains (1) summary
    PLN03096
    Location:6 → 399
    PLN03096; glyceraldehyde-3-phosphate dehydrogenase A; Provisional

  3. NM_001084060.1 → NP_001077529.1  glyceraldehyde 3-phosphate dehydrogenase A subunit 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001077529.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4HNZ6
    Conserved Domains (2) summary
    pfam00044
    Location:69 → 134
    Gp_dh_N; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
    pfam02800
    Location:139 → 295
    Gp_dh_C; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain

  4. NM_001123804.1 → NP_001117276.1  glyceraldehyde 3-phosphate dehydrogenase A subunit 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001117276.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2ET00
    Conserved Domains (3) summary
    PRK07403
    Location:16 → 350
    PRK07403; glyceraldehyde-3-phosphate dehydrogenase; Reviewed
    pfam00044
    Location:16 → 167
    Gp_dh_N; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
    pfam02800
    Location:172 → 328
    Gp_dh_C; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain

  5. NM_001198048.1 → NP_001184977.1  glyceraldehyde 3-phosphate dehydrogenase A subunit 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001184977.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2ET00
    Conserved Domains (3) summary
    PRK07403
    Location:16 → 350
    PRK07403; glyceraldehyde-3-phosphate dehydrogenase; Reviewed
    pfam00044
    Location:16 → 167
    Gp_dh_N; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
    pfam02800
    Location:172 → 328
    Gp_dh_C; Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LPW0.1

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