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LOX3 lipoxygenase 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838314, updated on 18-Sep-2024

Summary

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Official Symbol
LOX3
Official Full Name
lipoxygenase 3
Primary source
TAIR:AT1G17420
Locus tag
AT1G17420
See related
Araport:AT1G17420
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
Arabidopsis thaliana lipoxygenase 3; ATLOX3; F28G4.10; lipoxygenase 3
Summary
LOX3 encode a Lipoxygenase. Lipoxygenases (LOXs) catalyze the oxygenation of fatty acids (FAs).
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Genomic context

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See LOX3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Sequence:
Chromosome: 1; NC_003070.9 (5977323..5981521)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Nucleoside diphosphate kinase family protein Neighboring gene ncRNA Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene Transcription initiation factor TFIID subunit A Neighboring gene B-block binding subunit of TFIIIC

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mapping methyl jasmonate-mediated transcriptional reprogramming of metabolism and cell cycle progression in cultured Arabidopsis cells. Pauwels L, et al. Proc Natl Acad Sci U S A, 2008 Jan 29. PMID 18216250, Free PMC Article
  2. Absence of endo-1,4-β-glucanase KOR1 alters the jasmonate-dependent defence response to Pseudomonas syringae in Arabidopsis. López-Cruz J, et al. J Plant Physiol, 2014 Oct 15. PMID 25108263
  3. Arabidopsis lox3 lox4 double mutants are male sterile and defective in global proliferative arrest. Caldelari D, et al. Plant Mol Biol, 2011 Jan. PMID 21052784
  4. Systemic and intracellular responses to photooxidative stress in Arabidopsis. Rossel JB, et al. Plant Cell, 2007 Dec. PMID 18156220, Free PMC Article
  5. Identification and characterization of COI1-dependent transcription factor genes involved in JA-mediated response to wounding in Arabidopsis plants. Wang Z, et al. Plant Cell Rep, 2008 Jan. PMID 17786451

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. In conditions of red light-induced defence, Arabidopsis LOX activity and transcription levels of LOX2, LOX3, and LOX4 were both upregulated.
    Title: Phytochrome B-mediated activation of lipoxygenase modulates an excess red light-induced defence response in Arabidopsis.
  2. The jasmonic acid (JA) pathway was activated more in kor1-1 plants with an increase in the JA-biosynthesis gene LOX3 and a greater accumulation of JA. Upon infection the accumulation of JA and JA-isoleucine (JA-Ile) was higher than in wild-type plants.
    Title: Absence of endo-1,4-β-glucanase KOR1 alters the jasmonate-dependent defence response to Pseudomonas syringae in Arabidopsis.
  3. Data show that deficiency in LOX3(At1g17420) and LOX4 (At1g72520) causes developmental dysfunctions, compared to wild type, and lox3 lox4 double mutants are taller and develop more inflorescence shoots and flowers.
    Title: Arabidopsis lox3 lox4 double mutants are male sterile and defective in global proliferative arrest.
  4. AtLOX-2, AtLOX-3, AtLOX-4 and AtLOX-6 are 13S-lipoxygenases.
    Title: Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_101603.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables linoleate 13S-lipoxygenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within anther dehiscence IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within anther development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within defense response TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within jasmonic acid biosynthetic process TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within lipid oxidation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in oxylipin biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within pollen development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within response to fungus IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to high light intensity IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to jasmonic acid IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in response to wounding IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to wounding TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within stamen filament development IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
lipoxygenase 3
NP_564021.1
  • lipoxygenase 3 (LOX3); FUNCTIONS IN: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, lipoxygenase activity, iron ion binding, metal ion binding; INVOLVED IN: growth, response to fungus, jasmonic acid biosynthetic process, response to wounding, defense response; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Lipoxygenase, iron binding site (InterPro:IPR020833), Lipoxygenase, C-terminal (InterPro:IPR013819), Lipoxygenase, LH2 (InterPro:IPR001024), Lipase/lipooxygenase, PLAT/LH2 (InterPro:IPR008976), Lipoxygenase, conserved site (InterPro:IPR020834), Lipoxygenase (InterPro:IPR000907), Lipoxygenase, plant (InterPro:IPR001246); BEST Arabidopsis thaliana protein match is: PLAT/LH2 domain-containing lipoxygenase family protein (TAIR:AT1G72520.1); Has 1470 Blast hits to 1436 proteins in 179 species: Archae - 0; Bacteria - 76; Metazoa - 529; Fungi - 49; Plants - 787; Viruses - 0; Other Eukaryotes - 29 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    5977323..5981521
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101603.3 → NP_564021.1  lipoxygenase 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564021.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LNR3, Q9LQJ5, Q9SMW1
    UniProtKB/TrEMBL
    A0A5S9UV07, A0A654EAN8
    Conserved Domains (1) summary
    PLN02264
    Location:1 → 919
    PLN02264; lipoxygenase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LNR3.1

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