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Slc25a2 solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2 [ Mus musculus (house mouse) ]

Gene ID: 83885, updated on 2-Nov-2024

Summary

Official Symbol
Slc25a2provided by MGI
Official Full Name
solute carrier family 25 (mitochondrial carrier, ornithine transporter) member 2provided by MGI
Primary source
MGI:MGI:2137907
See related
Ensembl:ENSMUSG00000050304 AllianceGenome:MGI:2137907
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ornt2
Summary
Predicted to enable L-arginine transmembrane transporter activity; L-lysine transmembrane transporter activity; and L-ornithine transmembrane transporter activity. Predicted to be involved in L-alpha-amino acid transmembrane transport and ornithine metabolic process. Located in mitochondrion. Is expressed in medulla oblongata basal plate mantle layer and pons mantle layer. Orthologous to human SLC25A2 (solute carrier family 25 member 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See Slc25a2 in Genome Data Viewer
Location:
18 B3; 18 19.54 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (37770431..37771776, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (37637378..37638723, complement)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene protocadherin alpha 4B Neighboring gene predicted gene, 38666 Neighboring gene predicted gene, 38667 Neighboring gene STARR-seq mESC enhancer starr_44310 Neighboring gene STARR-seq mESC enhancer starr_44311 Neighboring gene protocadherin beta 21 Neighboring gene protocadherin beta 22 Neighboring gene STARR-seq mESC enhancer starr_44313 Neighboring gene STARR-seq mESC enhancer starr_44314 Neighboring gene STARR-positive B cell enhancer ABC_E4245 Neighboring gene protein UXT pseudogene Neighboring gene TATA-box binding protein associated factor 7

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables L-arginine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables L-lysine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
enables L-ornithine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables L-ornithine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in L-arginine transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in L-lysine transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in L-ornithine transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in mitochondrial L-ornithine transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in mitochondrial L-ornithine transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
involved_in ornithine metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mitochondrial ornithine transporter 2
Names
mitochondrial ornithine transporter
ornithine transporter 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159275.1NP_001152747.1  mitochondrial ornithine transporter 2

    See identical proteins and their annotated locations for NP_001152747.1

    Status: VALIDATED

    Source sequence(s)
    AK077159
    Consensus CDS
    CCDS50258.1
    UniProtKB/TrEMBL
    Q99ML6
    Related
    ENSMUSP00000052849.3, ENSMUST00000058635.5
    Conserved Domains (1) summary
    pfam00153
    Location:169261
    Mito_carr; Mitochondrial carrier protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    37770431..37771776 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)