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MNS3 alpha-mannosidase 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839879, updated on 18-Sep-2024

Summary

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Official Symbol
MNS3
Official Full Name
alpha-mannosidase 3
Primary source
TAIR:AT1G30000
Locus tag
AT1G30000
See related
Araport:AT1G30000
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
alpha-mannosidase 3; T1P2.10; T1P2_10
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Genomic context

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See MNS3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
6
Sequence:
Chromosome: 1; NC_003070.9 (10509156..10512558, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene choice-of-anchor C domain protein, putative (Protein of unknown function, DUF642) Neighboring gene prefoldin 6 Neighboring gene Intron maturase, type II family protein Neighboring gene hypothetical protein (Protein of unknown function, DUF538) Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A signal motif retains Arabidopsis ER-α-mannosidase I in the cis-Golgi and prevents enhanced glycoprotein ERAD. Schoberer J, et al. Nat Commun, 2019 Aug 16. PMID 31420549, Free PMC Article
  2. Class I alpha-mannosidases are required for N-glycan processing and root development in Arabidopsis thaliana. Liebminger E, et al. Plant Cell, 2009 Dec. PMID 20023195, Free PMC Article
  3. Separating Golgi Proteins from Cis to Trans Reveals Underlying Properties of Cisternal Localization. Parsons HT, et al. Plant Cell, 2019 Sep. PMID 31266899, Free PMC Article
  4. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
  5. Isolation and proteomic characterization of the Arabidopsis Golgi defines functional and novel components involved in plant cell wall biosynthesis. Parsons HT, et al. Plant Physiol, 2012 May. PMID 22430844, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

NM_001332879.1
NM_102740.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables alpha-mannosidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within N-glycan processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within root development IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus HDA PubMed 
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in Golgi apparatus ISM
Inferred from Sequence Model
more info
  
located_in Golgi medial cisterna HDA PubMed 
located_in endosome HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in trans-Golgi network HDA PubMed 

General protein information

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Preferred Names
alpha-mannosidase 3
NP_564345.1
  • alpha-mannosidase 3 (MNS3); CONTAINS InterPro DOMAIN/s: Glycoside hydrolase, family 47 (InterPro:IPR001382); BEST Arabidopsis thaliana protein match is: alpha-mannosidase 2 (TAIR:AT3G21160.1); Has 2086 Blast hits to 1880 proteins in 193 species: Archae - 0; Bacteria - 12; Metazoa - 798; Fungi - 875; Plants - 191; Viruses - 0; Other Eukaryotes - 210 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    10509156..10512558 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_102740.3 → NP_564345.1  alpha-mannosidase 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564345.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q93Y37, Q9C8R9
    UniProtKB/TrEMBL
    A0A178WR43, A0A5S9WFE4, A0A7G2DYY7
    Conserved Domains (1) summary
    pfam01532
    Location:135 → 620
    Glyco_hydro_47; Glycosyl hydrolase family 47

  2. NM_001332879.1 → NP_001320239.1  alpha-mannosidase 3 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AM79, A0A7G2DYY7
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q93Y37.1

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