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GA2OX2 gibberellin 2-oxidase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839883, updated on 18-Sep-2024

Summary

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Official Symbol
GA2OX2
Official Full Name
gibberellin 2-oxidase
Primary source
TAIR:AT1G30040
Locus tag
AT1G30040
See related
Araport:AT1G30040
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATGA2OX2; gibberellin 2-oxidase; GIBBERELLIN 2-OXIDASE 2; T1P2.6; T1P2_6
Summary
Encodes a gibberellin 2-oxidase that acts on C-19 gibberellins. AtGA2OX2 expression is responsive to cytokinin and KNOX activities.
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Genomic context

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See GA2OX2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
3
Sequence:
Chromosome: 1; NC_003070.9 (10537457..10540044)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Intron maturase, type II family protein Neighboring gene hypothetical protein (Protein of unknown function, DUF538) Neighboring gene pseudo Neighboring gene tropomyosin Neighboring gene COP1-interacting protein-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Plant-Specific Histone Deacetylases HDT1/2 Regulate GIBBERELLIN 2-OXIDASE2 Expression to Control Arabidopsis Root Meristem Cell Number. Li H, et al. Plant Cell, 2017 Sep. PMID 28855334, Free PMC Article
  2. Molecular cloning and functional expression of gibberellin 2- oxidases, multifunctional enzymes involved in gibberellin deactivation. Thomas SG, et al. Proc Natl Acad Sci U S A, 1999 Apr 13. PMID 10200325, Free PMC Article
  3. Regulation of hormone metabolism in Arabidopsis seeds: phytochrome regulation of abscisic acid metabolism and abscisic acid regulation of gibberellin metabolism. Seo M, et al. Plant J, 2006 Nov. PMID 17010113
  4. PIL5, a phytochrome-interacting bHLH protein, regulates gibberellin responsiveness by binding directly to the GAI and RGA promoters in Arabidopsis seeds. Oh E, et al. Plant Cell, 2007 Apr. PMID 17449805, Free PMC Article
  5. Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress. Lee TA, et al. Plant Cell, 2019 Nov. PMID 31519798, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These results suggest that by repressing the expression of GA2ox2, HDT1/2 likely fine-tune gibberellin metabolism.
    Title: Plant-Specific Histone Deacetylases HDT1/2 Regulate GIBBERELLIN 2-OXIDASE2 Expression to Control Arabidopsis Root Meristem Cell Number.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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NM_001036035.2
NM_102743.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables C-19 gibberellin 2-beta-dioxygenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables C-19 gibberellin 2-beta-dioxygenase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
involved_in gibberellin biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within gibberellin catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within response to red light IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to red or far red light IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
gibberellin 2-oxidase
NP_001031112.1
  • gibberellin 2-oxidase (GA2OX2); CONTAINS InterPro DOMAIN/s: Oxoglutarate/iron-dependent oxygenase (InterPro:IPR005123); BEST Arabidopsis thaliana protein match is: gibberellin 2-oxidase 3 (TAIR:AT2G34555.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_174296.1
  • gibberellin 2-oxidase (GA2OX2); CONTAINS InterPro DOMAIN/s: Isopenicillin N synthase (InterPro:IPR002283), Oxoglutarate/iron-dependent oxygenase (InterPro:IPR005123); BEST Arabidopsis thaliana protein match is: gibberellin 2-oxidase 3 (TAIR:AT2G34555.1); Has 8540 Blast hits to 8490 proteins in 994 species: Archae - 0; Bacteria - 1137; Metazoa - 84; Fungi - 1033; Plants - 4909; Viruses - 0; Other Eukaryotes - 1377 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    10537457..10540044
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_102743.3 → NP_174296.1  gibberellin 2-oxidase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_174296.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4I385, Q9XFR9
    UniProtKB/TrEMBL
    A0A178WMY6, A0A5S9WFL2
    Conserved Domains (1) summary
    PLN02156
    Location:1 → 340
    PLN02156; gibberellin 2-beta-dioxygenase

  2. NM_001036035.2 → NP_001031112.1  gibberellin 2-oxidase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031112.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WJC0
    Conserved Domains (2) summary
    pfam03171
    Location:180 → 253
    2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily
    pfam14226
    Location:31 → 125
    DIOX_N; non-haem dioxygenase in morphine synthesis N-terminal
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9XFR9.1

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