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SCL33 SC35-like splicing factor 33 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 841976, updated on 3-Nov-2024

Summary

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Official Symbol
SCL33
Official Full Name
SC35-like splicing factor 33
Primary source
TAIR:AT1G55310
Locus tag
AT1G55310
See related
Araport:AT1G55310
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
At-SCL33; ATSCL33; F7A10.26; F7A10.27; F7A10_26; SC35-like splicing factor 33; SC35-LIKE SPLICING FACTOR 33; SR33
Summary
Encodes a SR spliceosome protein that is localized to nuclear specks, interacts with SR45 and the U1-70K protein of the U1 snRNP, has sequence similar to human SC35 protein. Barta et al (2010) have proposed a nomenclature for Serine/Arginine-Rich Protein Splicing Factors (SR proteins): Plant Cell. 2010, 22:2926.
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Genomic context

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See SCL33 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
7
Sequence:
Chromosome: 1; NC_003070.9 (20629698..20633007)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene TBP-associated factor 7 Neighboring gene acyl-activating enzyme 18 Neighboring gene RNA polymerase II transcription mediator

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Tissue-specific expression and dynamic organization of SR splicing factors in Arabidopsis. Fang Y, et al. Mol Biol Cell, 2004 Jun. PMID 15034145, Free PMC Article
  2. An SC35-like protein and a novel serine/arginine-rich protein interact with Arabidopsis U1-70K protein. Golovkin M, et al. J Biol Chem, 1999 Dec 17. PMID 10593939
  3. Phosphothreonine 218 is required for the function of SR45.1 in regulating flower petal development in Arabidopsis. Zhang XN, et al. Plant Signal Behav, 2014. PMID 25763493, Free PMC Article
  4. Co-localisation studies of Arabidopsis SR splicing factors reveal different types of speckles in plant cell nuclei. Lorković ZJ, et al. Exp Cell Res, 2008 Oct 15. PMID 18674533
  5. Network of interactions of a novel plant-specific Arg/Ser-rich protein, atRSZ33, with atSC35-like splicing factors. Lopato S, et al. J Biol Chem, 2002 Oct 18. PMID 12176998

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001036118.4
NM_001198307.2
NM_001333699.1
NM_001333700.1
NM_001333702.1
NM_104406.6

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables RNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within mRNA splicing, via spliceosome IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in interchromatin granule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nuclear speck IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
SC35-like splicing factor 33
NP_001319238.1
  • SC35-like splicing factor 33 (SR33); FUNCTIONS IN: protein binding, RNA binding; INVOLVED IN: nuclear mRNA splicing, via spliceosome, RNA splicing; LOCATED IN: interchromatin granule, nuclear speck, nucleolus, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: SC35-like splicing factor 30A (TAIR:AT3G13570.1); Has 74071 Blast hits to 42895 proteins in 2604 species: Archae - 973; Bacteria - 11117; Metazoa - 35835; Fungi - 6236; Plants - 4620; Viruses - 230; Other Eukaryotes - 15060 (source: NCBI BLink).
NP_001319239.1
  • SC35-like splicing factor 33 (SR33); CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: SC35-like splicing factor 30A (TAIR:AT3G13570.1).
NP_564685.4
  • SC35-like splicing factor 33 (SR33); FUNCTIONS IN: protein binding, RNA binding; INVOLVED IN: nuclear mRNA splicing, via spliceosome, RNA splicing; LOCATED IN: interchromatin granule, nuclear speck, nucleolus, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: SC35-like splicing factor 30A (TAIR:AT3G13570.1); Has 74071 Blast hits to 42895 proteins in 2604 species: Archae - 973; Bacteria - 11117; Metazoa - 35835; Fungi - 6236; Plants - 4620; Viruses - 230; Other Eukaryotes - 15060 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    20629698..20633007
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001333701.1 → NP_001321067.1  SC35-like splicing factor 33 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178W693, A0A1P8APR8

  2. NM_104406.6 → NP_564685.4  SC35-like splicing factor 33 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564685.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    C0Z312, F4I090, F4I092, Q949P4, Q9C8A1, Q9SEU4
    UniProtKB/TrEMBL
    A0A654EK33
    Conserved Domains (2) summary
    COG0724
    Location:30 → 117
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cl17169
    Location:36 → 119
    RRM_SF; RNA recognition motif (RRM) superfamily

  3. NM_001333699.1 → NP_001319238.1  SC35-like splicing factor 33 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SEU4

  4. NM_001036118.4 → NP_001031195.4  SC35-like splicing factor 33 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031195.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SEU4
    Conserved Domains (2) summary
    COG0724
    Location:30 → 117
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cl17169
    Location:36 → 119
    RRM_SF; RNA recognition motif (RRM) superfamily

  5. NM_001333700.1 → NP_001319239.1  SC35-like splicing factor 33 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2H1ZEE9, A0A654EK33

  6. NM_001198307.2 → NP_001185236.2  SC35-like splicing factor 33 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178W6P9, A0A1P8APR4

  7. NM_001333702.1 → NP_001321066.1  SC35-like splicing factor 33 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178W6P9, A0A1P8APR4
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SEU4.1

Gene LinkOut

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