U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CPN60B chaperonin 60 beta [ Arabidopsis thaliana (thale cress) ]

Gene ID: 841996, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
CPN60B
Official Full Name
chaperonin 60 beta
Primary source
TAIR:AT1G55490
Locus tag
AT1G55490
See related
Araport:AT1G55490
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
chaperonin 60 beta; chaperonin-60beta1; CPN60BETA; Cpn60beta1; LEN1; LESION INITIATION 1; T5A14.11; T5A14_11
Summary
encodes the beta subunit of the chloroplast chaperonin 60, a homologue of bacterial GroEL. Mutants in this gene develops lesions on its leaves, expresses systemic acquired resistance (SAR) and develops accelerated cell death to heat shock stress. The protein has molecular chaperone activity for suppressing protein aggregation in vitro.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CPN60B in Genome Data Viewer
Location:
chromosome: 1
Exon count:
15
Sequence:
Chromosome: 1; NC_003070.9 (20715563..20719261, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene protein containing PDZ domain, a K-box domain, and a TPR region Neighboring gene evolutionarily conserved C-terminal region 4 Neighboring gene branched-chain alpha-keto acid decarboxylase E1 beta subunit Neighboring gene TATA binding protein 2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Isolation and characterization of genes encoding chaperonin 60 beta from Arabidopsis thaliana. Zabaleta E, et al. Gene, 1992 Feb 15. PMID 1347275
  2. Deletion of a chaperonin 60 beta gene leads to cell death in the Arabidopsis lesion initiation 1 mutant. Ishikawa A, et al. Plant Cell Physiol, 2003 Mar. PMID 12668771
  3. Association of Rubisco activase with chaperonin-60beta: a possible mechanism for protecting photosynthesis during heat stress. Salvucci ME. J Exp Bot, 2008. PMID 18353762
  4. Plastid chaperonin proteins Cpn60 alpha and Cpn60 beta are required for plastid division in Arabidopsis thaliana. Suzuki K, et al. BMC Plant Biol, 2009 Apr 6. PMID 19344532, Free PMC Article
  5. PAB is an assembly chaperone that functions downstream of chaperonin 60 in the assembly of chloroplast ATP synthase coupling factor 1. Mao J, et al. Proc Natl Acad Sci U S A, 2015 Mar 31. PMID 25775508, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Moderate reduction of Cpn60-beta protein levels impaired plastid division while severe loss abolished greening of plastids. [Cpn60-beta]
    Title: Plastid chaperonin proteins Cpn60 alpha and Cpn60 beta are required for plastid division in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

NM_001333710.1
NM_001333711.1
NM_001333712.1
NM_104424.2
NM_179480.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP-dependent protein folding chaperone IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within chaperone cofactor-dependent protein refolding IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within protein folding TAS
Traceable Author Statement
more info
  
involved_in protein refolding IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to cold IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within systemic acquired resistance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
NOT located_in Golgi apparatus RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in apoplast HDA PubMed 
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast NAS
Non-traceable Author Statement
more info
 PubMed 
located_in chloroplast envelope HDA PubMed 
located_in chloroplast stroma HDA PubMed 
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in cytosolic ribosome HDA PubMed 
located_in nucleus HDA PubMed 
located_in stromule IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
chaperonin 60 beta
NP_175945.1
  • chaperonin 60 beta (CPN60B); FUNCTIONS IN: protein binding; INVOLVED IN: protein folding, systemic acquired resistance, cell death, response to cold, chaperone mediated protein folding requiring cofactor; LOCATED IN: in 8 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Chaperonin Cpn60/TCP-1 (InterPro:IPR002423), Chaperonin Cpn60, conserved site (InterPro:IPR018370), Chaperonin Cpn60 (InterPro:IPR001844); BEST Arabidopsis thaliana protein match is: TCP-1/cpn60 chaperonin family protein (TAIR:AT3G13470.1); Has 34209 Blast hits to 34175 proteins in 8723 species: Archae - 804; Bacteria - 21846; Metazoa - 1741; Fungi - 1612; Plants - 841; Viruses - 2; Other Eukaryotes - 7363 (source: NCBI BLink).
NP_849811.1
  • chaperonin 60 beta (CPN60B); FUNCTIONS IN: protein binding; INVOLVED IN: protein folding, systemic acquired resistance, cell death, response to cold, chaperone mediated protein folding requiring cofactor; LOCATED IN: in 7 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Chaperonin Cpn60/TCP-1 (InterPro:IPR002423), Chaperonin Cpn60, conserved site (InterPro:IPR018370), Chaperonin Cpn60 (InterPro:IPR001844); BEST Arabidopsis thaliana protein match is: TCP-1/cpn60 chaperonin family protein (TAIR:AT3G13470.1); Has 34209 Blast hits to 34175 proteins in 8723 species: Archae - 804; Bacteria - 21846; Metazoa - 1741; Fungi - 1612; Plants - 841; Viruses - 2; Other Eukaryotes - 7363 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    20715563..20719261 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_179480.3 → NP_849811.1  chaperonin 60 beta [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849811.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B9DFS9, B9DHQ8, P21240, Q9SAV2
    UniProtKB/TrEMBL
    A0A178VIX7, A0A178W724, A0A5S9WM41, A0A5S9XBS6
    Conserved Domains (1) summary
    PLN03167
    Location:1 → 600
    PLN03167; Chaperonin-60 beta subunit; Provisional

  2. NM_001333712.1 → NP_001320637.1  chaperonin 60 beta [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B9DFS9, B9DHQ8, P21240, Q9SAV2
    UniProtKB/TrEMBL
    A0A178VIX7, A0A178W724, A0A5S9WM41, A0A5S9XBS6
    Conserved Domains (1) summary
    PLN03167
    Location:1 → 600
    PLN03167; Chaperonin-60 beta subunit; Provisional

  3. NM_001333711.1 → NP_001320638.1  chaperonin 60 beta [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B9DFS9, B9DHQ8, P21240, Q9SAV2
    UniProtKB/TrEMBL
    A0A178VIX7, A0A178W724, A0A5S9WM41, A0A5S9XBS6
    Conserved Domains (1) summary
    PLN03167
    Location:1 → 600
    PLN03167; Chaperonin-60 beta subunit; Provisional

  4. NM_001333710.1 → NP_001320639.1  chaperonin 60 beta [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B9DFS9, B9DHQ8, P21240, Q9SAV2
    UniProtKB/TrEMBL
    A0A178VIX7, A0A178W724, A0A5S9WM41, A0A5S9XBS6
    Conserved Domains (1) summary
    PLN03167
    Location:1 → 600
    PLN03167; Chaperonin-60 beta subunit; Provisional

  5. NM_104424.2 → NP_175945.1  chaperonin 60 beta [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_175945.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    B9DFS9, B9DHQ8, P21240, Q9SAV2
    UniProtKB/TrEMBL
    A0A178VIX7, A0A178W724, A0A5S9WM41, A0A5S9XBS6
    Conserved Domains (1) summary
    PLN03167
    Location:1 → 600
    PLN03167; Chaperonin-60 beta subunit; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P21240.3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools