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SAR1B secretion-associated RAS 1B [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842086, updated on 18-Sep-2024

Summary

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Official Symbol
SAR1B
Official Full Name
secretion-associated RAS 1B
Primary source
TAIR:AT1G56330
Locus tag
AT1G56330
See related
Araport:AT1G56330
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA SECRETION-ASSOCIATED RAS 1B; ATSAR1; ATSAR1B; ATSARA1B; F14G9.6; F14G9_6; SAR1; SARL; SECRETION-ASSOCIATED RAS 1; secretion-associated RAS 1B
Summary
Encodes a small GTP-binding protein implicated in ER to cis-Golgi transport of other proteins. A member of ARF-like GTPase family. A thaliana has 21 members, in two subfamilies, ARF and ARF-like (ARL) GTPases. The protein is found associated to the ER and free in the cytosol.
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Genomic context

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See SAR1B in Genome Data Viewer
Location:
chromosome: 1
Exon count:
3
Sequence:
Chromosome: 1; NC_003070.9 (21086501..21088554, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene CwfJ-like family protein Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene uncharacterized protein Neighboring gene calreticulin 1a Neighboring gene Pseudouridine synthase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis Sar1b is critical for pollen tube growth. Liang X, et al. Plant Mol Biol, 2024 May 29. PMID 38809410
  2. Elements proximal to and within the transmembrane domain mediate the organelle-to-organelle movement of bZIP28 under ER stress conditions. Srivastava R, et al. Plant J, 2012 Jun. PMID 22335396
  3. A putative Arabidopsis nucleoporin, AtNUP160, is critical for RNA export and required for plant tolerance to cold stress. Dong CH, et al. Mol Cell Biol, 2006 Dec. PMID 17030626, Free PMC Article
  4. Characterization of AtSEC12 and AtSAR1. Proteins likely involved in endoplasmic reticulum and Golgi transport. Bar-Peled M, et al. Plant Physiol, 1997 May. PMID 9159953, Free PMC Article
  5. Analysis of the small GTPase gene superfamily of Arabidopsis. Vernoud V, et al. Plant Physiol, 2003 Mar. PMID 12644670, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Arabidopsis Sar1b is critical for pollen tube growth.
    Title: Arabidopsis Sar1b is critical for pollen tube growth.
  2. NUP160 is critical for nucleocytoplasmic transport of mRNAs, plays important role in plant growth and flowering time regulation, and is required for cold stress tolerance.
    Title: A putative Arabidopsis nucleoporin, AtNUP160, is critical for RNA export and required for plant tolerance to cold stress.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_104512.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables GTP binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within endoplasmic reticulum to Golgi vesicle-mediated transport TAS
Traceable Author Statement
more info
 PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
secretion-associated RAS 1B
NP_176029.1
  • secretion-associated RAS 1B (SAR1B); FUNCTIONS IN: GTP binding; INVOLVED IN: ER to Golgi vesicle-mediated transport; LOCATED IN: cytosol, peripheral to membrane of membrane fraction, endoplasmic reticulum, plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Small GTP-binding protein (InterPro:IPR005225), Small GTPase SAR1-type (InterPro:IPR006687), ARF/SAR superfamily (InterPro:IPR006689); BEST Arabidopsis thaliana protein match is: secretion-associated RAS super family 2 (TAIR:AT4G02080.1); Has 6720 Blast hits to 6718 proteins in 371 species: Archae - 2; Bacteria - 32; Metazoa - 3237; Fungi - 1226; Plants - 1080; Viruses - 0; Other Eukaryotes - 1143 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    21086501..21088554 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_104512.3 → NP_176029.1  secretion-associated RAS 1B [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_176029.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q01474
    UniProtKB/TrEMBL
    A0A178WM97, A0A5S9TDR2, A0A5S9WQ64, A0A654E9N5
    Conserved Domains (1) summary
    smart00178
    Location:4 → 192
    SAR; Sar1p-like members of the Ras-family of small GTPases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q01474.1

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