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CPSF73-I cleavage and polyadenylation specificity factor 73-I [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842393, updated on 18-Sep-2024

Summary

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Official Symbol
CPSF73-I
Official Full Name
cleavage and polyadenylation specificity factor 73-I
Primary source
TAIR:AT1G61010
Locus tag
AT1G61010
See related
Araport:AT1G61010
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
cleavage and polyadenylation specificity factor 73-I; T7P1.15; T7P1_15
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Genomic context

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See CPSF73-I in Genome Data Viewer
Location:
chromosome: 1
Exon count:
7
Sequence:
Chromosome: 1; NC_003070.9 (22474267..22477765, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Glycine cleavage T-protein family Neighboring gene SCR-like 7 Neighboring gene S3 self-incompatibility locus-linked pollen protein Neighboring gene kinetochore protein Neighboring gene tRNA-Arg Neighboring gene WAPL (Wings apart-like protein regulation of heterochromatin) protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. snRNA 3' End Processing by a CPSF73-Containing Complex Essential for Development in Arabidopsis. Liu Y, et al. PLoS Biol, 2016 Oct. PMID 27780203, Free PMC Article
  2. Distinctive interactions of the Arabidopsis homolog of the 30 kD subunit of the cleavage and polyadenylation specificity factor (AtCPSF30) with other polyadenylation factor subunits. Rao S, et al. BMC Cell Biol, 2009 Jul 2. PMID 19573236, Free PMC Article
  3. The 73 kD subunit of the cleavage and polyadenylation specificity factor (CPSF) complex affects reproductive development in Arabidopsis. Xu R, et al. Plant Mol Biol, 2006 Jul. PMID 16897494
  4. Defective RNA processing enhances RNA silencing and influences flowering of Arabidopsis. Herr AJ, et al. Proc Natl Acad Sci U S A, 2006 Oct 10. PMID 17008405, Free PMC Article
  5. Unique features of plant cleavage and polyadenylation specificity factor revealed by proteomic studies. Zhao H, et al. Plant Physiol, 2009 Nov. PMID 19748916, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Two 73 kD subunits of the AtCPSF complex appear to have special functions during flower development.[CPSF73-I]
    Title: The 73 kD subunit of the cleavage and polyadenylation specificity factor (CPSF) complex affects reproductive development in Arabidopsis.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001036138.2
NM_001333924.1
NM_001333925.1
NM_104782.4
NM_179504.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within snRNA processing IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
cleavage and polyadenylation specificity factor 73-I
NP_001031215.1
  • cleavage and polyadenylation specificity factor 73-I (CPSF73-I); CONTAINS InterPro DOMAIN/s: Beta-Casp domain (InterPro:IPR022712), RNA-metabolising metallo-beta-lactamase (InterPro:IPR011108), Beta-lactamase-like (InterPro:IPR001279), Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term (InterPro:IPR021718); BEST Arabidopsis thaliana protein match is: cleavage and polyadenylation specificity factor 73 kDa subunit-II (TAIR:AT2G01730.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_001319278.1
  • cleavage and polyadenylation specificity factor 73-I (CPSF73-I); CONTAINS InterPro DOMAIN/s: Beta-Casp domain (InterPro:IPR022712), RNA-metabolising metallo-beta-lactamase (InterPro:IPR011108), Beta-lactamase-like (InterPro:IPR001279), Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term (InterPro:IPR021718); BEST Arabidopsis thaliana protein match is: cleavage and polyadenylation specificity factor 73 kDa subunit-II (TAIR:AT2G01730.1); Has 5076 Blast hits to 5016 proteins in 1410 species: Archae - 467; Bacteria - 2637; Metazoa - 590; Fungi - 276; Plants - 187; Viruses - 2; Other Eukaryotes - 917 (source: NCBI BLink).
NP_849835.1
  • cleavage and polyadenylation specificity factor 73-I (CPSF73-I); CONTAINS InterPro DOMAIN/s: Beta-Casp domain (InterPro:IPR022712), RNA-metabolising metallo-beta-lactamase (InterPro:IPR011108), Beta-lactamase-like (InterPro:IPR001279), Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term (InterPro:IPR021718); BEST Arabidopsis thaliana protein match is: cleavage and polyadenylation specificity factor 73 kDa subunit-II (TAIR:AT2G01730.1); Has 5076 Blast hits to 5016 proteins in 1410 species: Archae - 467; Bacteria - 2637; Metazoa - 590; Fungi - 276; Plants - 187; Viruses - 2; Other Eukaryotes - 917 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    22474267..22477765 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001036138.2 → NP_001031215.1  cleavage and polyadenylation specificity factor 73-I [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031215.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8VY18, Q9C952
    UniProtKB/TrEMBL
    A0A178WGJ2, A0A5S9WN75, A0A7G2E2C2
    Conserved Domains (3) summary
    COG1236
    Location:24 → 462
    YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
    cd16292
    Location:22 → 215
    CPSF3-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 3 and related proteins; MBL-fold metallo-hydrolase domain
    pfam11718
    Location:486 → 687
    CPSF73-100_C; Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term

  2. NM_179504.2 → NP_849835.1  cleavage and polyadenylation specificity factor 73-I [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_849835.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8VY18, Q9C952
    UniProtKB/TrEMBL
    A0A178WGJ2, A0A5S9WN75, A0A7G2E2C2
    Conserved Domains (3) summary
    COG1236
    Location:24 → 462
    YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
    cd16292
    Location:22 → 215
    CPSF3-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 3 and related proteins; MBL-fold metallo-hydrolase domain
    pfam11718
    Location:486 → 687
    CPSF73-100_C; Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term

  3. NM_001333924.1 → NP_001319278.1  cleavage and polyadenylation specificity factor 73-I [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8VY18, Q9C952
    UniProtKB/TrEMBL
    A0A178WGJ2, A0A5S9WN75, A0A7G2E2C2
    Conserved Domains (3) summary
    COG1236
    Location:24 → 462
    YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
    cd16292
    Location:22 → 215
    CPSF3-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 3 and related proteins; MBL-fold metallo-hydrolase domain
    pfam11718
    Location:486 → 687
    CPSF73-100_C; Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term

  4. NM_001333925.1 → NP_001321253.1  cleavage and polyadenylation specificity factor 73-I [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8VY18, Q9C952
    UniProtKB/TrEMBL
    A0A178WGJ2, A0A5S9WN75, A0A7G2E2C2
    Conserved Domains (3) summary
    COG1236
    Location:24 → 462
    YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
    cd16292
    Location:22 → 215
    CPSF3-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 3 and related proteins; MBL-fold metallo-hydrolase domain
    pfam11718
    Location:486 → 687
    CPSF73-100_C; Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term

  5. NM_104782.4 → NP_176297.1  cleavage and polyadenylation specificity factor 73-I [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_176297.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8VY18, Q9C952
    UniProtKB/TrEMBL
    A0A178WGJ2, A0A5S9WN75, A0A7G2E2C2
    Conserved Domains (3) summary
    COG1236
    Location:24 → 462
    YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
    cd16292
    Location:22 → 215
    CPSF3-like_MBL-fold; cleavage and polyadenylation specificity factor (CPSF) subunit 3 and related proteins; MBL-fold metallo-hydrolase domain
    pfam11718
    Location:486 → 687
    CPSF73-100_C; Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9C952.1

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