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UBC28 ubiquitin-conjugating enzyme 28 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 842728, updated on 18-Sep-2024

Summary

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Official Symbol
UBC28
Official Full Name
ubiquitin-conjugating enzyme 28
Primary source
TAIR:AT1G64230
Locus tag
AT1G64230
See related
Araport:AT1G64230
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F22C12.2; F22C12_2; ubiquitin-conjugating enzyme 28; UBIQUITIN-CONJUGATING ENZYME28
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Genomic context

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See UBC28 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
6
Sequence:
Chromosome: 1; NC_003070.9 (23833485..23835539)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Leucine-rich repeat protein kinase family protein Neighboring gene translocase of outer membrane 7 kDa subunit 2 Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis membrane-anchored ubiquitin-fold (MUB) proteins localize a specific subset of ubiquitin-conjugating (E2) enzymes to the plasma membrane. Dowil RT, et al. J Biol Chem, 2011 Apr 29. PMID 21345795, Free PMC Article
  2. Genome analysis and functional characterization of the E2 and RING-type E3 ligase ubiquitination enzymes of Arabidopsis. Kraft E, et al. Plant Physiol, 2005 Dec. PMID 16339806, Free PMC Article
  3. Arabidopsis scaffold protein RACK1A interacts with diverse environmental stress and photosynthesis related proteins. Kundu N, et al. Plant Signal Behav, 2013 May. PMID 23435172, Free PMC Article
  4. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812
  5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001036151.1
NM_001160973.1
NM_001160974.1
NM_001198379.1
NM_105097.9

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ubiquitin conjugating enzyme activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin-protein transferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
ubiquitin-conjugating enzyme 28
NP_001031228.1
  • ubiquitin-conjugating enzyme 28 (UBC28); FUNCTIONS IN: ubiquitin-protein ligase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: ubiquitin conjugating enzyme 8 (TAIR:AT5G41700.5); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_001154445.1
  • ubiquitin-conjugating enzyme 28 (UBC28); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: ubiquitin conjugating enzyme 9 (TAIR:AT4G27960.1); Has 10537 Blast hits to 10496 proteins in 399 species: Archae - 0; Bacteria - 4; Metazoa - 4600; Fungi - 2215; Plants - 1971; Viruses - 26; Other Eukaryotes - 1721 (source: NCBI BLink).
NP_001154446.1
  • ubiquitin-conjugating enzyme 28 (UBC28); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: ubiquitin conjugating enzyme 8 (TAIR:AT5G41700.5); Has 10460 Blast hits to 10419 proteins in 398 species: Archae - 0; Bacteria - 4; Metazoa - 4543; Fungi - 2213; Plants - 1965; Viruses - 26; Other Eukaryotes - 1709 (source: NCBI BLink).
NP_001185308.1
  • ubiquitin-conjugating enzyme 28 (UBC28); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: ubiquitin conjugating enzyme 8 (TAIR:AT5G41700.5).
NP_564828.1
  • ubiquitin-conjugating enzyme 28 (UBC28); FUNCTIONS IN: ubiquitin-protein ligase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: ubiquitin conjugating enzyme 8 (TAIR:AT5G41700.5); Has 10654 Blast hits to 10613 proteins in 404 species: Archae - 0; Bacteria - 4; Metazoa - 4603; Fungi - 2343; Plants - 1945; Viruses - 27; Other Eukaryotes - 1732 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    23833485..23835539
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_105097.9 → NP_564828.1  ubiquitin-conjugating enzyme 28 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_564828.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q94F47, Q9SH72
    UniProtKB/TrEMBL
    A0A178VAX4, A0A178WCS7, A0A5S9WRW9
    Conserved Domains (1) summary
    cl00154
    Location:1 → 146
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

  2. NM_001198379.1 → NP_001185308.1  ubiquitin-conjugating enzyme 28 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001185308.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4I5B8
    Conserved Domains (2) summary
    COG5078
    Location:1 → 189
    COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
    cl00154
    Location:1 → 188
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

  3. NM_001160973.1 → NP_001154445.1  ubiquitin-conjugating enzyme 28 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001154445.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4I5C0
    Conserved Domains (2) summary
    COG5078
    Location:1 → 156
    COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
    cl00154
    Location:1 → 155
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

  4. NM_001160974.1 → NP_001154446.1  ubiquitin-conjugating enzyme 28 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001154446.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4I5B8
    Conserved Domains (2) summary
    COG5078
    Location:1 → 189
    COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
    cl00154
    Location:1 → 188
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

  5. NM_001036151.1 → NP_001031228.1  ubiquitin-conjugating enzyme 28 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031228.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q94F47, Q9SH72
    UniProtKB/TrEMBL
    A0A178VAX4, A0A178WCS7, A0A5S9WRW9
    Conserved Domains (1) summary
    cl00154
    Location:1 → 146
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q94F47.1

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