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ABCG39 pleiotropic drug resistance 11 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 843013, updated on 18-Sep-2024

Summary

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Official Symbol
ABCG39
Official Full Name
pleiotropic drug resistance 11
Primary source
TAIR:AT1G66950
Locus tag
AT1G66950
See related
Araport:AT1G66950
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATP-binding cassette G39; ATPDR11; PDR11; pleiotropic drug resistance 11; PLEIOTROPIC DRUG RESISTANCE 11; T4O24.9; T4O24_9
Summary
Encodes a plasma membrane-localized ABC transporter. Confers tolerance to herbicide paraquat.
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Genomic context

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See ABCG39 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
20
Sequence:
Chromosome: 1; NC_003070.9 (24978121..24984619)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Protein kinase superfamily protein Neighboring gene kinase-like protein Neighboring gene Terpenoid cyclases family protein Neighboring gene SHV3-like 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Loss of AtPDR11, a plasma membrane-localized ABC transporter, confers paraquat tolerance in Arabidopsis thaliana. Xi J, et al. Plant J, 2012 Mar. PMID 22026747
  2. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157
  3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Loss-of-function mutations of AtPDR11 result in a paraquat resistance phenotype at the seedling stage due to reduced import of paraquat in Arabidopsis.
    Title: Loss of AtPDR11, a plasma membrane-localized ABC transporter, confers paraquat tolerance in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_105366.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables ATPase-coupled transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within response to reactive oxygen species IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within xenobiotic transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
pleiotropic drug resistance 11
NP_176867.2
  • pleiotropic drug resistance 11 (PDR11); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: drug transmembrane transport; LOCATED IN: membrane; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), Plant PDR ABC transporter associated (InterPro:IPR013581), ABC-2 type transporter (InterPro:IPR013525); BEST Arabidopsis thaliana protein match is: pleiotropic drug resistance 6 (TAIR:AT2G36380.1); Has 357151 Blast hits to 273757 proteins in 3981 species: Archae - 7090; Bacteria - 287486; Metazoa - 9208; Fungi - 6204; Plants - 5777; Viruses - 4; Other Eukaryotes - 41382 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    24978121..24984619
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_105366.4 → NP_176867.2  pleiotropic drug resistance 11 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_176867.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q7PC84, Q9C623, Q9FZI3
    UniProtKB/TrEMBL
    A0A178WE29
    Conserved Domains (6) summary
    cd03232
    Location:850 → 1088
    ABCG_PDR_domain2; Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters
    PLN03140
    Location:14 → 1454
    PLN03140; ABC transporter G family member; Provisional
    pfam01061
    Location:1183 → 1388
    ABC2_membrane; ABC-2 type transporter
    pfam08370
    Location:744 → 810
    PDR_assoc; Plant PDR ABC transporter associated
    pfam14510
    Location:94 → 169
    ABC_trans_N; ABC-transporter extracellular N-terminal
    cl21455
    Location:180 → 430
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7PC84.1

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