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Slco1a6 solute carrier organic anion transporter family, member 1a6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 84608, updated on 2-Nov-2024

Summary

Official Symbol
Slco1a6provided by RGD
Official Full Name
solute carrier organic anion transporter family, member 1a6provided by RGD
Primary source
RGD:69304
See related
EnsemblRapid:ENSRNOG00000030894 AllianceGenome:RGD:69304
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Oatp5; Slc21a13
Summary
Predicted to enable bile acid transmembrane transporter activity and sodium-independent organic anion transmembrane transporter activity. Involved in animal organ regeneration. Predicted to be located in plasma membrane. Predicted to be active in basolateral plasma membrane. Orthologous to human SLCO1A2 (solute carrier organic anion transporter family member 1A2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 536.5) See more
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Genomic context

See Slco1a6 in Genome Data Viewer
Location:
4q44
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (176803025..176848311, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (175072143..175107950, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (176345671..176390729, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene solute carrier organic anion transporter family, member 1a8 Neighboring gene solute carrier organic anion transporter family, member 1A5 Neighboring gene islet amyloid polypeptide Neighboring gene uncharacterized LOC102549024

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables bile acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables sodium-independent organic anion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in animal organ regeneration IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in bile acid and bile salt transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in sodium-independent organic anion transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
solute carrier organic anion transporter family member 1A6
Names
OATP-5
kidney-specific organic anion transporting polypeptide 5
organic anion transporting polypeptide 5
solute carrier family (organic anion transporter) member 13
solute carrier family 21 member 13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_130736.1NP_570092.1  solute carrier organic anion transporter family member 1A6

    See identical proteins and their annotated locations for NP_570092.1

    Status: PROVISIONAL

    Source sequence(s)
    AF053317
    UniProtKB/Swiss-Prot
    Q9QYE2
    UniProtKB/TrEMBL
    A0A8L2UMB7, A6IMS9
    Related
    ENSRNOP00000039792.4, ENSRNOT00000048367.4
    Conserved Domains (1) summary
    TIGR00805
    Location:1625
    oat; sodium-independent organic anion transporter

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    176803025..176848311 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063286766.1XP_063142836.1  solute carrier organic anion transporter family member 1A6 isoform X1

    UniProtKB/TrEMBL
    A0A8L2ULI3
  2. XM_063286767.1XP_063142837.1  solute carrier organic anion transporter family member 1A6 isoform X2