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VAC17 Vac17p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850296, updated on 28-Oct-2024

Summary

Official Symbol
VAC17
Official Full Name
Vac17p
Primary source
SGD:S000000568
Locus tag
YCL063W
See related
AllianceGenome:SGD:S000000568; FungiDB:YCL063W; VEuPathDB:YCL063W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YCL062W
Summary
Enables protein-membrane adaptor activity. Involved in vacuole inheritance. Located in fungal-type vacuole membrane. Part of Myo2p-Vac17p-Vac8p transport complex. [provided by Alliance of Genome Resources, Oct 2024]
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Genomic context

See VAC17 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_001135.5 (17290..18561)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene transcriptional co-activator mating type protein alpha Neighboring gene L-serine/L-threonine ammonia-lyase CHA1 Neighboring gene chromatin-modulating protein MRC1 Neighboring gene ribosome biosynthesis protein KRR1

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables protein-membrane adaptor activity IEA
Inferred from Electronic Annotation
more info
 
enables protein-membrane adaptor activity IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in vacuole inheritance IEA
Inferred from Electronic Annotation
more info
 
involved_in vacuole inheritance IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in vacuole inheritance IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in vacuole inheritance IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
part_of Myo2p-Vac17p-Vac8p transport complex IPI
Inferred from Physical Interaction
more info
PubMed 
located_in fungal-type vacuole membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
 
located_in vacuole IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
Vac17p
NP_009870.1
  • Phosphoprotein involved in vacuole inheritance; degraded in late M phase of the cell cycle; acts as a vacuole-specific receptor for myosin Myo2p; involved in regulation of asymmetric inheritance of aggregated/misfolded proteins and age reset

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001135.5 Reference assembly

    Range
    17290..18561
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178705.1NP_009870.1  TPA: Vac17p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009870.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VQV5, P25590, P25591
    UniProtKB/TrEMBL
    A6ZTD4, B3LU23, B5VEP9, N1P804
    Conserved Domains (1) summary
    pfam17321
    Location:6422
    Vac17; Vacuole-related protein 17