U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MRPL32 mitochondrial 54S ribosomal protein YmL32 [ Saccharomyces cerevisiae S288C ]

Gene ID: 850359, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
MRPL32
Official Full Name
mitochondrial 54S ribosomal protein YmL32
Primary source
SGD:S000000596
Locus tag
YCR003W
See related
AllianceGenome:SGD:S000000596; FungiDB:YCR003W; VEuPathDB:YCR003W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
bL32m
Summary
A structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL32 (mitochondrial ribosomal protein L32). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MRPL32 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_001135.5 (118620..119171)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene septin CDC10 Neighboring gene flavodoxin-like fold family protein Neighboring gene citrate (Si)-synthase CIT2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001135.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The C-terminal extension domain of Saccharomyces cerevisiae MrpL32, a homolog of ribosomal protein L32, functions in trans to support mitochondrial translation. Woogeng IN, et al. Genes Genet Syst, 2018 Jul 13. PMID 29343666
  2. Presequence-dependent folding ensures MrpL32 processing by the m-AAA protease in mitochondria. Bonn F, et al. EMBO J, 2011 May 24. PMID 21610694, Free PMC Article
  3. The m-AAA protease defective in hereditary spastic paraplegia controls ribosome assembly in mitochondria. Nolden M, et al. Cell, 2005 Oct 21. PMID 16239145
  4. Quantitative proteomics identifies redox switches for global translation modulation by mitochondrially produced reactive oxygen species. Topf U, et al. Nat Commun, 2018 Jan 22. PMID 29358734, Free PMC Article
  5. Extended N-terminal sequencing of proteins of the large ribosomal subunit from yeast mitochondria. Grohmann L, et al. FEBS Lett, 1991 Jun 17. PMID 2060626

See all (47) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Through a series of C-terminally truncated mrpl32 (mrpl32DeltaC)gene, MrpL32DeltaC derivatives exhibited temperature-sensitive (ts) growth on medium with non-fermentable carbon sources. Furthermore, the CE domain of MrpL32, expressed separately from MrpL32DeltaC, could rescue the ts phenotype of mutants by improving mitochondrial protein synthesis.
    Title: The C-terminal extension domain of Saccharomyces cerevisiae MrpL32, a homolog of ribosomal protein L32, functions in trans to support mitochondrial translation.
  2. Presequence-assisted folding of MrpL32 requires import of the MrpL32 precursor before maturation occurs, this explains the post-translocational processing by the m-AAA protease rather than co-translocational cleavage by mitochondrial processing peptidase.
    Title: Presequence-dependent folding ensures MrpL32 processing by the m-AAA protease in mitochondria.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation IC
Inferred by Curator
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
part_of ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
mitochondrial 54S ribosomal protein YmL32
NP_009929.1
  • Mitochondrial ribosomal protein of the large subunit; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001135.5 Reference assembly

    Range
    118620..119171
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178716.1 → NP_009929.1  TPA: mitochondrial 54S ribosomal protein YmL32 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009929.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VR13, P25348
    UniProtKB/TrEMBL
    B3LU75, B5VEV1, C8Z488, G2WA21, N1PAP8
    Conserved Domains (1) summary
    pfam01783
    Location:72 → 120
    Ribosomal_L32p; Ribosomal L32p protein family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25348.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools
Miscellaneous