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CTR86 Ctr86p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850421, updated on 18-Sep-2024

Summary

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Official Symbol
CTR86
Official Full Name
Ctr86p
Primary source
SGD:S000000650
Locus tag
YCR054C
See related
AllianceGenome:SGD:S000000650; FungiDB:YCR054C; VEuPathDB:YCR054C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be involved in threonine biosynthetic process. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 10. Orthologous to human ATXN10 (ataxin 10). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See CTR86 in Genome Data Viewer
Location:
chromosome: III
Exon count:
1
Sequence:
Chromosome: III; NC_001135.5 (218376..220067, complement)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene Rsc6p Neighboring gene threonine synthase THR4 Neighboring gene snoRNA-binding rRNA-processing protein PWP2 Neighboring gene Yih1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001135.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Analysis of the THR4 region on chromosome III of the yeast Saccharomyces cerevisiae. Mannhaupt G, et al. Yeast, 1990 Jul-Aug. PMID 2204248
  2. Large-scale phenotypic analysis--the pilot project on yeast chromosome III. Rieger KJ, et al. Yeast, 1997 Dec. PMID 9509574
  3. 14-3-3 Protein Bmh1 triggers short-range compaction of mitotic chromosomes by recruiting sirtuin deacetylase Hst2. Jain N, et al. J Biol Chem, 2021 Jan-Jun. PMID 33187982, Free PMC Article
  4. The complete DNA sequence of yeast chromosome III. Oliver SG, et al. Nature, 1992 May 7. PMID 1574125
  5. The catalytic activity of the translation termination factor methyltransferase Mtq2-Trm112 complex is required for large ribosomal subunit biogenesis. Lacoux C, et al. Nucleic Acids Res, 2020 Dec 2. PMID 33166396, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus HDA PubMed 

General protein information

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Preferred Names
Ctr86p
NP_009983.1
  • Essential hypothetical protein; with orthologs in Ashbya gossypii and Candida albicans; similar to human ATXN10, mutations in which cause spinocerebellar ataxia type 10; codon usage corresponds to that observed for yeast genes expressed at low levels; relative distribution to the nucleus increases upon DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001135.5 Reference assembly

    Range
    218376..220067 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178768.1 → NP_009983.1  TPA: Ctr86p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009983.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VR62, P25355
    UniProtKB/TrEMBL
    A6ZTN3, B3LUB7, B5VEZ2, C7GJT2, C8Z4E6, G2WA69
    Conserved Domains (1) summary
    pfam09759
    Location:446 → 544
    Atx10homo_assoc; Spinocerebellar ataxia type 10 protein domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25355.1

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