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HMRA1 Hmra1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850459, updated on 17-May-2024

Summary

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Gene symbol
HMRA1
Gene description
Hmra1p
Primary source
FungiDB:YCR097W
Locus tag
YCR097W
See related
SGD:S000000694; AllianceGenome:SGD:S000000694; VEuPathDB:YCR097W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YCR097WB
Summary
Enables transcription corepressor activity. Involved in regulation of mating-type specific transcription, DNA-templated. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See HMRA1 in Genome Data Viewer
Location:
chromosome: III
Exon count:
3
Sequence:
Chromosome: III; NC_001135.5 (293835..294321)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene homeodomain mating type protein a2 Neighboring gene tRNA-Thr Neighboring gene Git1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001135.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Engineered improvements in DNA-binding function of the MATa1 homeodomain reveal structural changes involved in combinatorial control. Hart B, et al. J Mol Biol, 2002 Feb 15. PMID 11851335
  2. Conditional silencing: the HMRE mating-type silencer exerts a rapidly reversible position effect on the yeast HSP82 heat shock gene. Lee S, et al. Mol Cell Biol, 1993 Feb. PMID 8423797, Free PMC Article
  3. Splicing and spliceosome formation of the yeast MATa1 transcript require a minimum distance from the 5' splice site to the internal branch acceptor site. Köhrer K, et al. Nucleic Acids Res, 1988 Oct 25. PMID 3054807, Free PMC Article
  4. Role of intron splicing in the function of the MATa1 gene of Saccharomyces cerevisiae. Ner SS, et al. Mol Cell Biol, 1989 Nov. PMID 2574822, Free PMC Article
  5. A synthetic silencer mediates SIR-dependent functions in Saccharomyces cerevisiae. McNally FJ, et al. Mol Cell Biol, 1991 Nov. PMID 1922068, Free PMC Article

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables transcription corepressor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of mating-type specific transcription, DNA-templated IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Hmra1p
NP_010021.1
  • Silenced copy of a1 at HMR; homeobox corepressor that interacts with Alpha2p to repress haploid-specific gene transcription in diploid cells

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001135.5 Reference assembly

    Range
    293835..294321
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178804.1 → NP_010021.1  TPA: Hmra1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010021.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VR98, P01366, P09091, P0CY10, P0CY11, Q06724
    UniProtKB/TrEMBL
    B3LUF0, C7GSB0, C8Z4D0
    Conserved Domains (1) summary
    smart00389
    Location:70 → 126
    HOX; Homeodomain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0CY11.1

Gene LinkOut

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