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RPL22B ribosomal 60S subunit protein L22B [ Saccharomyces cerevisiae S288C ]

Gene ID: 850509, updated on 2-Nov-2024

Summary

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Official Symbol
RPL22B
Official Full Name
ribosomal 60S subunit protein L22B
Primary source
SGD:S000006436
Locus tag
YFL034C-A
See related
AllianceGenome:SGD:S000006436; FungiDB:YFL034C-A; VEuPathDB:YFL034C-A
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
YFL035C-B
Summary
A structural constituent of ribosome. Involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Orthologous to several human genes including RPL22L1 (ribosomal protein L22 like 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See RPL22B in Genome Data Viewer
Location:
chromosome: VI
Exon count:
2
Sequence:
Chromosome: VI; NC_001138.5 (64243..64932, complement)

Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase Neighboring gene Mob2p Neighboring gene Mil1p Neighboring gene protein kinase RIM15

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001138.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Conserved codon composition of ribosomal protein coding genes in Escherichia coli, Mycobacterium tuberculosis and Saccharomyces cerevisiae: lessons from supervised machine learning in functional genomics. Lin K, et al. Nucleic Acids Res, 2002 Jun 1. PMID 12034849, Free PMC Article
  2. Rpl22 is required for IME1 mRNA translation and meiotic induction in S. cerevisiae. Kim SJ, et al. Cell Div, 2016. PMID 27478489, Free PMC Article
  3. Introns provide a platform for intergenic regulatory feedback of RPL22 paralogs in yeast. Abrhámová K, et al. PLoS One, 2018. PMID 29304067, Free PMC Article
  4. Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins. Chan CT, et al. Nat Commun, 2012 Jul 3. PMID 22760636, Free PMC Article
  5. Translational control of one-carbon metabolism underpins ribosomal protein phenotypes in cell division and longevity. Maitra N, et al. Elife, 2020 May 20. PMID 32432546, Free PMC Article

See all (50) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cytoplasmic translation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cytoplasmic translation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal 60S subunit protein L22B
NP_116619.1
  • Ribosomal 60S subunit protein L22A; required for translation of long 5' UTR of IME1 mRNA and meiotic entry; autoregulates splicing of its pre-m-RNA; homologous to mammalian ribosomal protein L22, no bacterial homolog; RPL22B has a paralog, RPL22A, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001138.5 Reference assembly

    Range
    64243..64932 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184310.1 → NP_116619.1  TPA: ribosomal 60S subunit protein L22B [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_116619.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VTJ6, P56628
    UniProtKB/TrEMBL
    A7A205, B3LUH7, C8Z7P8, G2WDA7, N1PA18
    Conserved Domains (1) summary
    pfam01776
    Location:16 → 110
    Ribosomal_L22e; Ribosomal L22e protein family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P56628.2

Gene LinkOut

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