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WWM1 Wwm1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850538, updated on 18-Sep-2024

Summary

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Official Symbol
WWM1
Official Full Name
Wwm1p
Primary source
SGD:S000001884
Locus tag
YFL010C
See related
AllianceGenome:SGD:S000001884; FungiDB:YFL010C; VEuPathDB:YFL010C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be involved in apoptotic process. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See WWM1 in Genome Data Viewer
Location:
chromosome: VI
Exon count:
1
Sequence:
Chromosome: VI; NC_001138.5 (115108..115743, complement)

Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene hexose transporter HXT10 Neighboring gene Aua1p Neighboring gene SCF ubiquitin ligase complex subunit CDC4 Neighboring gene cohesin subunit SMC1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001138.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A metacaspase of Trypanosoma brucei causes loss of respiration competence and clonal death in the yeast Saccharomyces cerevisiae. Szallies A, et al. FEBS Lett, 2002 Apr 24. PMID 12062425
  2. A caspase-related protease regulates apoptosis in yeast. Madeo F, et al. Mol Cell, 2002 Apr. PMID 11983181
  3. Highly hydrophilic proteins in prokaryotes and eukaryotes are common during conditions of water deficit. Garay-Arroyo A, et al. J Biol Chem, 2000 Feb 25. PMID 10681550
  4. A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes. Stevenson LF, et al. Proc Natl Acad Sci U S A, 2001 Mar 27. PMID 11274415, Free PMC Article
  5. The influence of HMF and furfural on redox-balance and energy-state of xylose-utilizing Saccharomyces cerevisiae. Ask M, et al. Biotechnol Biofuels, 2013 Feb 15. PMID 23409974, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
  
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Wwm1p
NP_570898.1
  • WW domain containing hypothetical protein; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes G1 phase growth arrest and clonal death that is suppressed by overexpression of MCA1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001138.5 Reference assembly

    Range
    115108..115743 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179956.1 → NP_570898.1  TPA: Wwm1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_570898.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VTM0, P43582
    UniProtKB/TrEMBL
    A7A229, B3LUK0, C7GY99, C8Z7S7
    Conserved Domains (1) summary
    pfam00397
    Location:12 → 41
    WW; WW domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P43582.1

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