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putative amidotransferase [ Saccharomyces cerevisiae S288C ]

Gene ID: 850817, updated on 2-Nov-2024

Summary

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Official Full Name
putative amidotransferase
Primary source
SGD:S000004116
Locus tag
YLR126C
See related
AllianceGenome:SGD:S000004116; FungiDB:YLR126C; VEuPathDB:YLR126C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable transferase activity. Predicted to be involved in intracellular monoatomic cation homeostasis. Located in nuclear periphery. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (394765..395520, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene anaphase promoting complex subunit 2 Neighboring gene NEDD8 ligase DCN1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Disruption and functional analysis of six ORFs on chromosome XII of saccharomyces cerevisiae: YLR124w, YLR125w, YLR126c, YLR127c, YLR128w and YLR129w. Willer M, et al. Yeast, 2000 Nov. PMID 11054824
  2. Exploratory and confirmatory gene expression profiling of mac1Delta. De Freitas JM, et al. J Biol Chem, 2004 Feb 6. PMID 14534306
  3. Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications. Nitika, et al. PLoS Biol, 2022 Oct. PMID 36269765, Free PMC Article
  4. Functional analysis with a barcoder yeast gene overexpression system. Douglas AC, et al. G3 (Bethesda), 2012 Oct. PMID 23050238, Free PMC Article
  5. Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins. Fromont-Racine M, et al. Yeast, 2000 Jun 30. PMID 10900456, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glutamine metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular monoatomic cation homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nuclear periphery IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
putative amidotransferase
NP_013227.1
  • Putative glutamine amidotransferase; has Aft1p-binding motif in the promoter; may be involved in copper and iron homeostasis; YLR126C is not an essential protein; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    394765..395520 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182013.1 → NP_013227.1  TPA: putative amidotransferase [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013227.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VYC1, Q12288
    UniProtKB/TrEMBL
    A7A125, B3LT87, B5VN57, C7GQC9, C8ZD95, G2WIW5, N1NZP3
    Conserved Domains (1) summary
    cd01741
    Location:5 → 200
    GATase1_1; Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12288.1

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