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MSC3 Msc3p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850916, updated on 7-Jul-2024

Summary

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Gene symbol
MSC3
Gene description
Msc3p
Primary source
FungiDB:YLR219W
Locus tag
YLR219W
See related
SGD:S000004209; AllianceGenome:SGD:S000004209; VEuPathDB:YLR219W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in reciprocal meiotic recombination. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See MSC3 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (574151..576337)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase CPR6 Neighboring gene Coa4p Neighboring gene Ccc1p Neighboring gene Rsa3p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Seg1 controls eisosome assembly and shape. Moreira KE, et al. J Cell Biol, 2012 Aug 6. PMID 22869600, Free PMC Article
  2. Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination. Thompson DA, et al. Genetics, 1999 Oct. PMID 10511544, Free PMC Article
  3. A role for eisosomes in maintenance of plasma membrane phosphoinositide levels. Fröhlich F, et al. Mol Biol Cell, 2014 Sep 15. PMID 25057013, Free PMC Article
  4. Nicotinamide induces Fob1-dependent plasmid integration into chromosome XII in Saccharomyces cerevisiae. Tripathi K, et al. FEMS Yeast Res, 2012 Dec. PMID 22909099
  5. Unifying fluorescence microscopy and mass spectrometry for studying protein complexes in cells. Deng C, et al. Mol Cell Proteomics, 2009 Jun. PMID 19269952, Free PMC Article

See all (40) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in DNA recombination IEA
Inferred from Electronic Annotation
more info
  
involved_in meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in reciprocal meiotic recombination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Msc3p
NP_013320.1
  • hypothetical protein; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; msc3 mutants are defective in directing meiotic recombination events to homologous chromatids; potential Cdc28p substrate; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    574151..576337
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182106.1 → NP_013320.1  TPA: Msc3p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013320.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VYL9, Q05812, Q7LIF4
    UniProtKB/TrEMBL
    A0A8H4BZM5, C7GIU7, C8ZDI3, N1P1C8
    Conserved Domains (2) summary
    PHA03255
    Location:573 → 718
    PHA03255; BDLF3; Provisional
    cl27202
    Location:207 → 384
    Mpp10; Mpp10 protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q05812.1

Gene LinkOut

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