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RPS1A ribosomal 40S subunit protein S1A [ Saccharomyces cerevisiae S288C ]

Gene ID: 851162, updated on 3-Nov-2024

Summary

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Official Symbol
RPS1A
Official Full Name
ribosomal 40S subunit protein S1A
Primary source
SGD:S000004433
Locus tag
YLR441C
See related
AllianceGenome:SGD:S000004433; FungiDB:YLR441C; VEuPathDB:YLR441C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RP10A
Summary
Predicted to be a structural constituent of ribosome. Involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of 90S preribosome. Orthologous to human RPS3A (ribosomal protein S3A). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See RPS1A in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (1018141..1018908, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene mitochondrial 54S ribosomal protein YmL4 Neighboring gene Sec39p Neighboring gene chromatin-silencing protein SIR3 Neighboring gene Ecm7p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A gene family homologous to the S-phase specific gene in higher plants is essential for cell proliferation in Saccharomyces cerevisiae. Ito M, et al. FEBS Lett, 1992 Apr 13. PMID 1451783
  2. Structure and regulation of a Candida albicans RP10 gene which encodes an immunogenic protein homologous to Saccharomyces cerevisiae ribosomal protein 10. Swoboda RK, et al. J Bacteriol, 1995 Mar. PMID 7868597, Free PMC Article
  3. Structure of the 80S ribosome-Xrn1 nuclease complex. Tesina P, et al. Nat Struct Mol Biol, 2019 Apr. PMID 30911188
  4. The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2. Schopf FH, et al. Mol Cell, 2019 Apr 4. PMID 30876805
  5. Heavy metal sensitivities of gene deletion strains for ITT1 and RPS1A connect their activities to the expression of URE2, a key gene involved in metal detoxification in yeast. Moteshareie H, et al. PLoS One, 2018. PMID 30231023, Free PMC Article

See all (121) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This study reports on the finding of two genes, ITT1, an inhibitor of translation termination, and RPS1A, a small ribosomal protein, that when deleted yeast cells exhibit similar metal sensitivity phenotypes to gene deletion strain for URE2.
    Title: Heavy metal sensitivities of gene deletion strains for ITT1 and RPS1A connect their activities to the expression of URE2, a key gene involved in metal detoxification in yeast.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of 90S preribosome HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic small ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal 40S subunit protein S1A
NP_013546.1
  • Ribosomal protein of the small (40S) subunit; homologous to mammalian ribosomal protein S3A, no bacterial homolog; RPS1A has a paralog, RPS1B, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    1018141..1018908 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182329.1 → NP_013546.1  TPA: ribosomal 40S subunit protein S1A [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013546.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A7A1W1, B3RHV0, B5VNY0, C7GSL4, D6VZ76, P33442
    UniProtKB/TrEMBL
    G2WJQ2, N1P1Y6
    Conserved Domains (1) summary
    pfam01015
    Location:15 → 221
    Ribosomal_S3Ae; Ribosomal S3Ae family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P33442.2

Gene LinkOut

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