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BRE4 Bre4p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851367, updated on 2-Nov-2024

Summary

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Official Symbol
BRE4
Official Full Name
Bre4p
Primary source
SGD:S000002390
Locus tag
YDL231C
See related
AllianceGenome:SGD:S000002390; FungiDB:YDL231C; VEuPathDB:YDL231C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in endocytosis. Located in cell periphery. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See BRE4 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (38867..42244, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Mfg1p Neighboring gene olichyl-diphosphooligosaccharide--protein glycotransferase OST4 Neighboring gene tyrosine protein phosphatase PTP1 Neighboring gene Hsp70 family ATPase SSB1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification and characterization of Saccharomyces cerevisiae mutants defective in fluid-phase endocytosis. Wiederkehr A, et al. Yeast, 2001 Jun. PMID 11378903
  2. Identification of yeast deletion strains that are hypersensitive to brefeldin A or monensin, two drugs that affect intracellular transport. Murén E, et al. Yeast, 2001 Jan 30. PMID 11169758
  3. A genomic approach for the identification and classification of genes involved in cell wall formation and its regulation in Saccharomyces cerevisiae. de Groot PW, et al. Comp Funct Genomics, 2001. PMID 18628907, Free PMC Article
  4. Variations of the C2H2 zinc finger motif in the yeast genome and classification of yeast zinc finger proteins. Böhm S, et al. Nucleic Acids Res, 1997 Jun 15. PMID 9171100, Free PMC Article
  5. A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking. Aguilar PS, et al. Nat Struct Mol Biol, 2010 Jul. PMID 20526336, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in endocytosis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Bre4p
NP_010050.1
  • Zinc finger protein containing five transmembrane domains; null mutant exhibits strongly fragmented vacuoles and sensitivity to brefeldin A, a drug which is known to affect intracellular transport

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    38867..42244 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180291.1 → NP_010050.1  TPA: Bre4p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010050.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRC5, Q07660
    UniProtKB/TrEMBL
    B3LHA7, N1PA97
    Conserved Domains (2) summary
    pfam10337
    Location:148 → 279
    ArAE_2_N; Putative ER transporter, 6TM, N-terminal
    pfam13515
    Location:724 → 855
    FUSC_2; Fusaric acid resistance protein-like
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q07660.1

Gene LinkOut

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