U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TMA17 Tma17p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851448, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
TMA17
Official Full Name
Tma17p
Primary source
SGD:S000002268
Locus tag
YDL110C
See related
AllianceGenome:SGD:S000002268; FungiDB:YDL110C; VEuPathDB:YDL110C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
ADC17
Summary
Enables protein-macromolecule adaptor activity. Involved in fatty acid biosynthetic process and proteasome regulatory particle assembly. Located in cytoplasm and nucleus. Part of fatty acid synthase complex. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See TMA17 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (264512..264964, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene tRNA (guanosine(18)-2'-O)-methyltransferase Neighboring gene exosome non-catalytic core subunit RRP42 Neighboring gene putative lipase Neighboring gene TFIIH complex serine/threonine-protein kinase subunit KIN28

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase. Singh K, et al. Cell, 2020 Mar 19. PMID 32160528
  2. Actin remodelling controls proteasome homeostasis upon stress. Williams TD, et al. Nat Cell Biol, 2022 Jul. PMID 35739319, Free PMC Article
  3. Proteomic analysis of recombinant Saccharomyces cerevisiae upon iron deficiency induced via human H-ferritin production. Seo HY, et al. J Microbiol Biotechnol, 2008 Aug. PMID 18756096
  4. Proteomic analysis revealed the roles of YRR1 deletion in enhancing the vanillin resistance of Saccharomyces cerevisiae. Cao W, et al. Microb Cell Fact, 2021 Jul 23. PMID 34301255, Free PMC Article
  5. An inducible chaperone adapts proteasome assembly to stress. Hanssum A, et al. Mol Cell, 2014 Aug 21. PMID 25042801, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Distinct TORC1 signalling branches regulate Adc17 proteasome assembly chaperone expression.
    Title: Distinct TORC1 signalling branches regulate Adc17 proteasome assembly chaperone expression.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular function regulator activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein-macromolecule adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein-macromolecule adaptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in proteasome regulatory particle assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteasome regulatory particle assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in proteasome regulatory particle assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of fatty acid synthase complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus HDA PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Tma17p
NP_010173.1
  • Regulatory gamma subunit of fatty acid synthase (FAS); ATPase dedicated chaperone that adapts proteasome assembly to stress; induced upon stress; interacts with Rpt6p to assist its pairing to Rpt3p and early steps in proteasome biogenesis; associates with ribosomes; heterozygous deletion demonstrated increases in chromosome instability in a rad9 deletion background; protein abundance is decreased upon intracellular iron depletion

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    264512..264964 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180169.1 → NP_010173.1  TPA: Tma17p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010173.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRP0, Q12513
    UniProtKB/TrEMBL
    A6ZXL9, B3LH01, C7GJK6, C8Z6J4, G2WC52, N1P7L9
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12513.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools