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MSS2 Mss2p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851451, updated on 2-Nov-2024

Summary

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Official Symbol
MSS2
Official Full Name
Mss2p
Primary source
SGD:S000002265
Locus tag
YDL107W
See related
AllianceGenome:SGD:S000002265; FungiDB:YDL107W; VEuPathDB:YDL107W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in protein insertion into mitochondrial inner membrane from matrix. Located in mitochondrial matrix. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See MSS2 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (268921..269976)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene putative lipase Neighboring gene TFIIH complex serine/threonine-protein kinase subunit KIN28 Neighboring gene Pho2p Neighboring gene Smc5-Smc6 complex subunit NSE4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The nuclear-encoded MSS2 gene is involved in the expression of the mitochondrial cytochrome-c oxidase subunit 2 (Cox2). Simon M, et al. Biochim Biophys Acta, 1995 Feb 14. PMID 7857963
  2. Cox18p is required for export of the mitochondrially encoded Saccharomyces cerevisiae Cox2p C-tail and interacts with Pnt1p and Mss2p in the inner membrane. Saracco SA, et al. Mol Biol Cell, 2002 Apr. PMID 11950926, Free PMC Article
  3. The sequence of a 20.3 kb DNA fragment from the left arm of Saccharomyces cerevisiae chromosome IV contains the KIN28, MSS2, PHO2, POL3 and DUN1 genes, and six new open reading frames. Saiz JE, et al. Yeast, 1996 Sep. PMID 8896274
  4. Peripheral mitochondrial inner membrane protein, Mss2p, required for export of the mitochondrially coded Cox2p C tail in Saccharomyces cerevisiae. Broadley SA, et al. Mol Cell Biol, 2001 Nov. PMID 11604502, Free PMC Article
  5. Translocation of mitochondrially synthesized Cox2 domains from the matrix to the intermembrane space. Fiumera HL, et al. Mol Cell Biol, 2007 Jul. PMID 17452441, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in protein insertion into mitochondrial inner membrane from matrix IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in protein insertion into mitochondrial inner membrane from matrix IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein insertion into mitochondrial inner membrane from matrix IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial matrix IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Mss2p
NP_010176.1
  • Peripherally bound inner membrane protein of the mitochondrial matrix; involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    268921..269976
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180166.1 → NP_010176.1  TPA: Mss2p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010176.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRP3, P40990
    UniProtKB/TrEMBL
    G2WC55, N1PA92
    Conserved Domains (1) summary
    TIGR02917
    Location:136 → 240
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40990.2

Gene LinkOut

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