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RTK1 putative serine/threonine protein kinase RTK1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851536, updated on 18-Sep-2024

Summary

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Official Symbol
RTK1
Official Full Name
putative serine/threonine protein kinase RTK1
Primary source
SGD:S000002183
Locus tag
YDL025C
See related
AllianceGenome:SGD:S000002183; FungiDB:YDL025C; VEuPathDB:YDL025C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and protein phosphorylation. Located in cell periphery and cellular bud neck. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See RTK1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (405344..407206, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene serine/threonine/tyrosine protein kinase MPS1 Neighboring gene Mrx9p Neighboring gene putative acid phosphatase DIA3 Neighboring gene uncharacterized protein Neighboring gene tRNA-Ala

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unsupervised clustering of subcellular protein expression patterns in high-throughput microscopy images reveals protein complexes and functional relationships between proteins. Handfield LF, et al. PLoS Comput Biol, 2013. PMID 23785265, Free PMC Article
  2. Manipulating cell flocculation-associated protein kinases in Saccharomyces cerevisiae enables improved stress tolerance and efficient cellulosic ethanol production. Ye PL, et al. Bioresour Technol, 2022 Mar. PMID 35134528
  3. Reduction of the P5A-ATPase Spf1p phosphoenzyme by a Ca2+-dependent phosphatase. Corradi GR, et al. PLoS One, 2020. PMID 32353073, Free PMC Article
  4. Transcriptional activation of the general amino acid permease gene per1 by the histone deacetylase Clr6 Is regulated by Oca2 kinase. Kaufmann I, et al. Mol Cell Biol, 2010 Jul. PMID 20404084, Free PMC Article
  5. A proteomic strategy for gaining insights into protein sumoylation in yeast. Denison C, et al. Mol Cell Proteomics, 2005 Mar. PMID 15542864

See all (57) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables histone H2AS1 kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell periphery IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cellular bud neck IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
putative serine/threonine protein kinase RTK1
NP_010259.1
  • Putative protein kinase, potentially phosphorylated by Cdc28p; interacts with ribosome biogenesis factors, Cka2, Gus1 and Arc1; protein abundance increases in response to DNA replication stress

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    405344..407206 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180084.1 → NP_010259.1  TPA: putative serine/threonine protein kinase RTK1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010259.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRW6, Q12100
    UniProtKB/TrEMBL
    A6ZXU5, N1P4C6
    Conserved Domains (1) summary
    cd13994
    Location:308 → 575
    STKc_HAL4_like; Catalytic domain of Fungal Halotolerance protein 4-like Serine/Threonine kinases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12100.1

Gene LinkOut

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