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CPP3 cysteine-rich palmitoylated domain-containing protein CPP3 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851604, updated on 2-Nov-2024

Summary

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Official Symbol
CPP3
Official Full Name
cysteine-rich palmitoylated domain-containing protein CPP3
Primary source
SGD:S000007234
Locus tag
YDR034W-B
See related
AllianceGenome:SGD:S000007234; FungiDB:YDR034W-B; VEuPathDB:YDR034W-B
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Located in plasma membrane. Is active in cell periphery and vacuolar membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See CPP3 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (521314..521469)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene tRNA-Gln Neighboring gene 3-deoxy-7-phosphoheptulonate synthase ARO3 Neighboring gene mitochondrial 37S ribosomal protein EHD3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The YBR056W-A and Its Ortholog YDR034W-B of S. cerevisiae Belonging to CYSTM Family Participate in Manganese Stress Overcoming. Zvonarev A, et al. Genes (Basel), 2023 Apr 27. PMID 37239347, Free PMC Article
  2. Palmitoylation of CYSTM (CYSPD) proteins in yeast. Giolito ML, et al. J Biol Chem, 2024 Feb. PMID 38159851, Free PMC Article
  3. Dissection and design of yeast prions. Osherovich LZ, et al. PLoS Biol, 2004 Apr. PMID 15045026, Free PMC Article
  4. CYSTM, a novel cysteine-rich transmembrane module with a role in stress tolerance across eukaryotes. Venancio TM, et al. Bioinformatics, 2010 Jan 15. PMID 19933165, Free PMC Article
  5. The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. Jacq C, et al. Nature, 1997 May 29. PMID 9169867

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The YBR056W-A and Its Ortholog YDR034W-B of S. cerevisiae Belonging to CYSTM Family Participate in Manganese Stress Overcoming.
    Title: The YBR056W-A and Its Ortholog YDR034W-B of S. cerevisiae Belonging to CYSTM Family Participate in Manganese Stress Overcoming.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
is_active_in cell periphery IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in vacuolar membrane IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
cysteine-rich palmitoylated domain-containing protein CPP3
NP_010319.3
  • Tail-anchored plasma membrane (PM) protein; C-terminal palmitoylation is required for membrane anchoring and protein stability; PM localization is polarized to the daughter cell; also localizes to the vacuolar membrane; may be involved in response to stress; upregulated by toxic concentrations of heavy metal ions and alkali; contains a conserved cysteine rich palmitoylated domain (CYSPD, aka CYSTM); CPP3 has a paralog, MNC1, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    521314..521469
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184327.3 → NP_010319.3  TPA: cysteine-rich palmitoylated domain-containing protein CPP3 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010319.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VS22, Q6Q5X2
    UniProtKB/TrEMBL
    A6ZY02, B3LGN1, C7GQ12, C8Z4V6, G2WAE0
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6Q5X2.1

Gene LinkOut

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