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EHD3 mitochondrial 37S ribosomal protein EHD3 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851606, updated on 9-Jun-2024

Summary

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Gene symbol
EHD3
Gene description
mitochondrial 37S ribosomal protein EHD3
Primary source
FungiDB:YDR036C
Locus tag
YDR036C
See related
SGD:S000002443; AllianceGenome:SGD:S000002443; VEuPathDB:YDR036C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
mS47
Summary
Enables 3-hydroxyisobutyryl-CoA hydrolase activity. A structural constituent of ribosome. Predicted to be involved in valine catabolic process. Located in mitochondrion. Part of mitochondrial small ribosomal subunit. Orthologous to human HIBCH (3-hydroxyisobutyryl-CoA hydrolase). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See EHD3 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (523211..524713, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene cysteine-rich palmitoylated domain-containing protein CPP3 Neighboring gene 3-deoxy-7-phosphoheptulonate synthase ARO3 Neighboring gene lysine--tRNA ligase KRS1 Neighboring gene putative Na(+)-exporting P-type ATPase ENA5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The biochemistry of peroxisomal beta-oxidation in the yeast Saccharomyces cerevisiae. Hiltunen JK, et al. FEMS Microbiol Rev, 2003 Apr. PMID 12697341
  2. Functional analysis of six ORFs from Saccharomyces cerevisiae chromosome IV: two-spored asci produced by disruptant of YDR027c and strain-dependent DNA heterogeneity around YDR036c. Aittamaa M, et al. Yeast, 2001 Jul. PMID 11447599
  3. Identification and characterization of Saccharomyces cerevisiae mutants defective in fluid-phase endocytosis. Wiederkehr A, et al. Yeast, 2001 Jun. PMID 11378903
  4. Assessing systems properties of yeast mitochondria through an interaction map of the organelle. Perocchi F, et al. PLoS Genet, 2006 Oct 20. PMID 17054397, Free PMC Article
  5. Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Reinders J, et al. Mol Cell Proteomics, 2007 Nov. PMID 17761666

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables 3-hydroxyisobutyryl-CoA hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 3-hydroxyisobutyryl-CoA hydrolase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 3-hydroxyisobutyryl-CoA hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in branched-chain amino acid catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial translation IC
Inferred by Curator
more info
 PubMed 
involved_in valine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of mitochondrial small ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial 37S ribosomal protein EHD3
NP_010321.1
  • 3-hydroxyisobutyryl-CoA hydrolase; member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    523211..524713 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180344.1 → NP_010321.1  TPA: mitochondrial 37S ribosomal protein EHD3 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010321.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VS24, P28817, Q66RH2
    UniProtKB/TrEMBL
    A0A8H8UMV6, A6ZY04, B3LGM9, C7GQ14, C8Z4V8
    Conserved Domains (1) summary
    pfam16113
    Location:48 → 386
    ECH_2; Enoyl-CoA hydratase/isomerase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P28817.2

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