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MRX14 putative mitochondrial 54S ribosomal protein [ Saccharomyces cerevisiae S288C ]

Gene ID: 851692, updated on 2-Nov-2024

Summary

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Official Symbol
MRX14
Official Full Name
putative mitochondrial 54S ribosomal protein
Primary source
SGD:S000002522
Locus tag
YDR115W
See related
AllianceGenome:SGD:S000002522; FungiDB:YDR115W; VEuPathDB:YDR115W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
bL34m
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion and nucleus. Orthologous to human MRPL34 (mitochondrial ribosomal protein L34). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See MRX14 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (682175..682492)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene alanine transaminase ALT2 Neighboring gene securin Neighboring gene uncharacterized protein Neighboring gene mitochondrial 54S ribosomal protein MRPL1 Neighboring gene Tma64p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mitochondrial ribosome bL34 mutants present diminished translation of cytochrome c oxidase subunits. Guedes-Monteiro RF, et al. Cell Biol Int, 2018 Jun. PMID 29160602, Free PMC Article
  2. Proteomic profiling of the mitochondrial ribosome identifies Atp25 as a composite mitochondrial precursor protein. Woellhaf MW, et al. Mol Biol Cell, 2016 Oct 15. PMID 27582385, Free PMC Article
  3. The Antifungal Plant Defensin HsAFP1 from Heuchera sanguinea Induces Apoptosis in Candida albicans. Aerts AM, et al. Front Microbiol, 2011. PMID 21993350, Free PMC Article
  4. Functional discovery via a compendium of expression profiles. Hughes TR, et al. Cell, 2000 Jul 7. PMID 10929718
  5. Structure of the yeast mitochondrial large ribosomal subunit. Amunts A, et al. Science, 2014 Mar 28. PMID 24675956, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation ISA
Inferred from Sequence Alignment
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit ISA
Inferred from Sequence Alignment
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus HDA PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative mitochondrial 54S ribosomal protein
NP_010400.1
  • Putative mitochondrial ribosomal protein of the large subunit; required for respiratory growth and for efficient translation of mitochondrial COX1 and COX3; conditional mutant has reduced cytochrome c oxidase activity; protein increases in abundance and relocalizes to the plasma membrane upon DNA replication stress; contains and N-terminal mitochondrial targeting sequence; similar to E. coli L34 ribosomal protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    682175..682492
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180423.1 → NP_010400.1  TPA: putative mitochondrial 54S ribosomal protein [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010400.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSA0, Q04598
    UniProtKB/TrEMBL
    A6ZY76, B3LGG2, C7GIM2, C8Z531, G2WAL6, N1P6C0
    Conserved Domains (1) summary
    pfam00468
    Location:63 → 104
    Ribosomal_L34; Ribosomal protein L34
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q04598.1

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