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PAM1 Pam1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851838, updated on 1-Aug-2024

Summary

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Gene symbol
PAM1
Gene description
Pam1p
Primary source
FungiDB:YDR251W
Locus tag
YDR251W
See related
SGD:S000002659; AllianceGenome:SGD:S000002659; VEuPathDB:YDR251W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable oxidoreductase activity. Involved in pseudohyphal growth. Located in cellular bud neck and cellular bud tip. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See PAM1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (960614..963106)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene gluconokinase Neighboring gene uncharacterized protein Neighboring gene CCR4-NOT core subunit BTT1 Neighboring gene Met32p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional characteristics of Svl3 and Pam1 that are required for proper cell wall formation in yeast cells. Jin Y, et al. Yeast, 2020 Jul. PMID 32491201
  2. Overexpression of yeast PAM1 gene permits survival without protein phosphatase 2A and induces a filamentous phenotype. Hu GZ, et al. J Biol Chem, 1994 Feb 4. PMID 8106383
  3. Differentiated gene expression in cells within yeast colonies. Mináriková L, et al. Exp Cell Res, 2001 Dec 10. PMID 11716542
  4. Osw2 is required for proper assembly of glucan and/or mannan layers of the yeast spore wall. Pan HP, et al. J Biochem, 2018 Apr 1. PMID 29211891
  5. Identification of novel genes responsible for ethanol and/or thermotolerance by transposon mutagenesis in Saccharomyces cerevisiae. Kim HS, et al. Appl Microbiol Biotechnol, 2011 Aug. PMID 21556919

See all (43) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Functional characteristics of Svl3 and Pam1 that are required for proper cell wall formation in yeast cells.
    Title: Functional characteristics of Svl3 and Pam1 that are required for proper cell wall formation in yeast cells.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in pseudohyphal growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cellular bud HDA PubMed 
located_in cellular bud neck HDA PubMed 
located_in cellular bud neck IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cellular bud tip IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Pam1p
NP_010537.3
  • Essential hypothetical protein; exhibits variable expression during colony morphogenesis; overexpression permits survival without protein phosphatase 2A, inhibits growth, and induces a filamentous phenotype; PAM1 has a paralog, SVL3, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    960614..963106
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180559.3 → NP_010537.3  TPA: Pam1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010537.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSN1, P37304, Q03789
    UniProtKB/TrEMBL
    A6ZYK3, N1P6Y6
    Conserved Domains (1) summary
    COG3883
    Location:363 → 435
    CwlO1; Uncharacterized N-terminal domain of peptidoglycan hydrolase CwlO [Function unknown]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P37304.2

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