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RPL37B ribosomal 60S subunit protein L37B [ Saccharomyces cerevisiae S288C ]

Gene ID: 852111, updated on 18-Sep-2024

Summary

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Official Symbol
RPL37B
Official Full Name
ribosomal 60S subunit protein L37B
Primary source
SGD:S000002908
Locus tag
YDR500C
See related
AllianceGenome:SGD:S000002908; FungiDB:YDR500C; VEuPathDB:YDR500C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable RNA binding activity. Involved in cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Part of cytosolic large ribosomal subunit and preribosome, large subunit precursor. Orthologous to human RPL37 (ribosomal protein L37). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See RPL37B in Genome Data Viewer
Location:
chromosome: IV
Exon count:
2
Sequence:
Chromosome: IV; NC_001136.10 (1450198..1450853, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Sec20p Neighboring gene Lcd1p Neighboring gene Plm2p Neighboring gene methionine adenosyltransferase SAM2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Shortest-path network analysis is a useful approach toward identifying genetic determinants of longevity. Managbanag JR, et al. PLoS One, 2008. PMID 19030232, Free PMC Article
  2. Overexpression of budding yeast protein phosphatase Ppz1 impairs translation. Calafí C, et al. Biochim Biophys Acta Mol Cell Res, 2020 Aug. PMID 32339526
  3. Yeast polypeptide exit tunnel ribosomal proteins L17, L35 and L37 are necessary to recruit late-assembling factors required for 27SB pre-rRNA processing. Gamalinda M, et al. Nucleic Acids Res, 2013 Feb 1. PMID 23268442, Free PMC Article
  4. Sir2 deletion prevents lifespan extension in 32 long-lived mutants. Delaney JR, et al. Aging Cell, 2011 Dec. PMID 21902802, Free PMC Article
  5. Direct mass spectrometric analysis of intact proteins of the yeast large ribosomal subunit using capillary LC/FTICR. Lee SW, et al. Proc Natl Acad Sci U S A, 2002 Apr 30. PMID 11983894, Free PMC Article

See all (50) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IC
Inferred by Curator
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Process Evidence Code Pubs
involved_in cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of preribosome, large subunit precursor IDA
Inferred from Direct Assay
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
part_of ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal 60S subunit protein L37B
NP_010788.1
  • Ribosomal 60S subunit protein L37B; required for processing of 27SB pre-rRNA and formation of stable 66S assembly intermediates; protein abundance increases in response to DNA replication stress; homologous to mammalian ribosomal protein L37, no bacterial homolog; RPL37B has a paralog, RPL37A, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1450198..1450853 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180808.1 → NP_010788.1  TPA: ribosomal 60S subunit protein L37B [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010788.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VTC2, P51402
    UniProtKB/TrEMBL
    A6ZZ89, B3LFG7, C8Z657, G2WBM8, N1PAL4
    Conserved Domains (1) summary
    PTZ00073
    Location:1 → 83
    PTZ00073; 60S ribosomal protein L37; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P51402.2

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