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PSP1 Psp1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852116, updated on 2-Nov-2024

Summary

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Official Symbol
PSP1
Official Full Name
Psp1p
Primary source
SGD:S000002913
Locus tag
YDR505C
See related
AllianceGenome:SGD:S000002913; FungiDB:YDR505C; VEuPathDB:YDR505C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
GIN5
Summary
Enables mRNA binding activity. Located in P-body. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See PSP1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1456695..1459220, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene phosphatidate phosphatase LPP1 Neighboring gene Spg3p Neighboring gene putative oxidoreductase Neighboring gene tRNA-Leu

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Screening and identification of yeast sequences that cause growth inhibition when overexpressed. Akada R, et al. Mol Gen Genet, 1997 Apr 16. PMID 9150260
  2. Suppressors of the temperature sensitivity of DNA polymerase alpha mutations in Saccharomyces cerevisiae. Formosa T, et al. Mol Gen Genet, 1998 Feb. PMID 9529527
  3. A PhotoClick cholesterol-based quantitative proteomics screen for cytoplasmic sterol-binding proteins in Saccharomyces cerevisiae. Chauhan N, et al. Yeast, 2020 Jan. PMID 31758572
  4. Dosage rescue by UBC4 restores cell wall integrity in Saccharomyces cerevisiae lacking the myosin type II gene MYO1. Díaz-Blanco NL, et al. Yeast, 2007 Apr. PMID 17397110, Free PMC Article
  5. Distinct roles of Rho1, Cdc42, and Cyk3 in septum formation and abscission during yeast cytokinesis. Onishi M, et al. J Cell Biol, 2013 Jul 22. PMID 23878277, Free PMC Article

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables mRNA binding HDA PubMed 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in P-body IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Psp1p
NP_010793.2
  • Asn and gln rich hypothetical protein; high-copy suppressor of POL1 (DNA polymerase alpha) and partial suppressor of CDC2 (polymerase delta) and CDC6 (pre-RC loading factor) mutations; overexpression results in growth inhibition; capable of forming the prion [PSP1+]; PSP1 has a paralog, YLR177W, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1456695..1459220 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180813.2 → NP_010793.2  TPA: Psp1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010793.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VTC7, P50896
    UniProtKB/TrEMBL
    B3LFG3, G2WBN3, N1PAL5
    Conserved Domains (1) summary
    COG1774
    Location:581 → 838
    YaaT; Cell fate regulator YaaT, PSP1 superfamily (controls sporulation, competence, biofilm development) [Signal transduction mechanisms]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P50896.2

Gene LinkOut

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