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CDC27 anaphase promoting complex subunit CDC27 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852194, updated on 2-Nov-2024

Summary

Official Symbol
CDC27
Official Full Name
anaphase promoting complex subunit CDC27
Primary source
SGD:S000000180
Locus tag
YBL084C
See related
AllianceGenome:SGD:S000000180; FungiDB:YBL084C; VEuPathDB:YBL084C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
APC3; SNB1
Summary
Contributes to ubiquitin protein ligase activity. Involved in anaphase-promoting complex-dependent catabolic process and protein ubiquitination. Located in nuclear periphery. Part of anaphase-promoting complex. Orthologous to human CDC27 (cell division cycle 27). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See CDC27 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (67169..69445, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Boi1p Neighboring gene dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase Neighboring gene uncharacterized protein

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
contributes_to ubiquitin protein ligase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in anaphase-promoting complex-dependent catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in anaphase-promoting complex-dependent catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in anaphase-promoting complex-dependent catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell division IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in metaphase/anaphase transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein ubiquitination IDA
Inferred from Direct Assay
more info
PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
involved_in protein ubiquitination IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
part_of anaphase-promoting complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of anaphase-promoting complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of anaphase-promoting complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nuclear periphery IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
anaphase promoting complex subunit CDC27
NP_009469.2
  • Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    67169..69445 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178324.2NP_009469.2  TPA: anaphase promoting complex subunit CDC27 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009469.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VPS0, P38042
    UniProtKB/TrEMBL
    G2W8S9, N1P6P8
    Conserved Domains (3) summary
    TIGR02917
    Location:500741
    PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
    sd00006
    Location:540568
    TPR; TPR repeat [structural motif]
    pfam12895
    Location:39126
    ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3