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SEF1 Sef1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852214, updated on 2-Nov-2024

Summary

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Official Symbol
SEF1
Official Full Name
Sef1p
Primary source
SGD:S000000162
Locus tag
YBL066C
See related
AllianceGenome:SGD:S000000162; FungiDB:YBL066C; VEuPathDB:YBL066C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See SEF1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (96669..100115, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene ribose phosphate diphosphokinase subunit PRS4 Neighboring gene ubiquitin-specific protease UBP13 Neighboring gene thioredoxin peroxidase PRX1 Neighboring gene Kip1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Novel Hybrid Iron Regulation Network Combines Features from Pathogenic and Nonpathogenic Yeasts. Gerwien F, et al. mBio, 2016 Oct 18. PMID 27795405, Free PMC Article
  2. Kluyveromyces lactis SEF1 and its Saccharomyces cerevisiae homologue bypass the unknown essential function, but not the mitochondrial RNase P function, of the S. cerevisiae RPM2 gene. Groom KR, et al. Yeast, 1998 Jan 15. PMID 9483797
  3. Sequencing and functional analysis of a 32,560 bp segment on the left arm of yeast chromosome II. Identification of 26 open reading frames, including the KIP1 and SEC17 genes. Scherens B, et al. Yeast, 1993 Dec. PMID 8154187
  4. Yeast Nap1-binding protein Nbp2p is required for mitotic growth at high temperatures and for cell wall integrity. Ohkuni K, et al. Genetics, 2003 Oct. PMID 14573466, Free PMC Article
  5. Chromatin remodeling complexes are involvesd in the regulation of ethanol production during static fermentation in budding yeast. Fang T, et al. Genomics, 2020 Mar. PMID 31618673

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transcription cis-regulatory region binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in biological_process ND
No biological Data available
more info
  
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
involved_in sporulation resulting in formation of a cellular spore IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Sef1p
NP_009487.2
  • Putative transcription factor; has homolog in Kluyveromyces lactis

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    96669..100115 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178306.1 → NP_009487.2  TPA: Sef1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009487.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VPT5, P34228
    UniProtKB/TrEMBL
    B3LNK0, B5VDS2, C7GNA1, C8Z3T0
    Conserved Domains (2) summary
    smart00066
    Location:51 → 96
    GAL4; GAL4-like Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain
    pfam04082
    Location:353 → 577
    Fungal_trans; Fungal specific transcription factor domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P34228.4

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