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MRPL16 mitochondrial 54S ribosomal protein YmL47 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852242, updated on 17-May-2024

Summary

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Gene symbol
MRPL16
Gene description
mitochondrial 54S ribosomal protein YmL47
Primary source
FungiDB:YBL038W
Locus tag
YBL038W
See related
SGD:S000000134; AllianceGenome:SGD:S000000134; VEuPathDB:YBL038W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RML16; uL16m
Summary
A structural constituent of ribosome. Involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL16 (mitochondrial ribosomal protein L16). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See MRPL16 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (146187..146885)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Min6p Neighboring gene CTP synthase URA7 Neighboring gene Apl3p Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of the yeast nuclear gene for the mitochondrial homologue of bacterial ribosomal protein L16. Pan C, et al. Nucleic Acids Res, 1995 Sep 25. PMID 7478995, Free PMC Article
  2. Defects in mitochondrial fatty acid synthesis result in failure of multiple aspects of mitochondrial biogenesis in Saccharomyces cerevisiae. Kursu VA, et al. Mol Microbiol, 2013 Nov. PMID 24102902, Free PMC Article
  3. Genomewide analysis reveals novel pathways affecting endoplasmic reticulum homeostasis, protein modification and quality control. Copic A, et al. Genetics, 2009 Jul. PMID 19433630, Free PMC Article
  4. Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae. Kitakawa M, et al. Eur J Biochem, 1997 Apr 15. PMID 9151978
  5. Functional discovery via a compendium of expression profiles. Hughes TR, et al. Cell, 2000 Jul 7. PMID 10929718

See all (44) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial translation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mitochondrial 54S ribosomal protein YmL47
NP_009515.1
  • Mitochondrial ribosomal protein of the large subunit; homologous to bacterial L16 ribosomal protein; synthetic lethality with hac1 mutation suggests a possible role in synthesis of precursors for protein glycosylation

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    146187..146885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178278.1 → NP_009515.1  TPA: mitochondrial 54S ribosomal protein YmL47 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009515.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VPW1, P38064, Q07216
    UniProtKB/TrEMBL
    A0A6A5Q1J7, G2W8X0, N1P9Q5
    Conserved Domains (1) summary
    cl00353
    Location:42 → 174
    Ribosomal_L16_L10e; L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with the 30S subunit, ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38064.1

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