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RRN10 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852256, updated on 11-Sep-2024

Summary

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Official Symbol
RRN10
Primary source
SGD:S000000121
Locus tag
YBL025W
See related
AllianceGenome:SGD:S000000121; FungiDB:YBL025W; VEuPathDB:YBL025W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables RNA polymerase I cis-regulatory region sequence-specific DNA binding activity and RNA polymerase I general transcription initiation factor activity. Involved in nucleolar large rRNA transcription by RNA polymerase I. Located in nucleolus. Part of RNA polymerase I upstream activating factor complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (171481..171918)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene ribosomal 60S subunit protein L19B Neighboring gene Sm-like protein LSM2 Neighboring gene tRNA (cytosine-C5-)-methyltransferase Neighboring gene MCM DNA helicase complex subunit MCM2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Construction of a Saccharomyces cerevisiae strain with a high level of RNA. Chuwattanakul V, et al. J Biosci Bioeng, 2011 Jul. PMID 21571588
  2. Increased transcription of NOP15, involved in ribosome biogenesis in Saccharomyces cerevisiae, enhances the production yield of RNA as a source of nucleotide seasoning. Chuwattanakul V, et al. J Biosci Bioeng, 2012 Jul. PMID 22608550
  3. Increased transcription of RPL40A and RPL40B is important for the improvement of RNA production in Saccharomyces cerevisiae. Khatun F, et al. J Biosci Bioeng, 2013 Oct. PMID 23669742
  4. Interaction of TATA-binding protein with upstream activation factor is required for activated transcription of ribosomal DNA by RNA polymerase I in Saccharomyces cerevisiae in vivo. Steffan JS, et al. Mol Cell Biol, 1998 Jul. PMID 9632758, Free PMC Article
  5. Histones H3 and H4 are components of upstream activation factor required for the high-level transcription of yeast rDNA by RNA polymerase I. Keener J, et al. Proc Natl Acad Sci U S A, 1997 Dec 9. PMID 9391047, Free PMC Article

See all (47) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA polymerase I cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase I cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA polymerase I cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase I general transcription initiation factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in nucleolar large rRNA transcription by RNA polymerase I IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in nucleolar large rRNA transcription by RNA polymerase I IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in nucleolar large rRNA transcription by RNA polymerase I IEA
Inferred from Electronic Annotation
more info
  
involved_in nucleolar large rRNA transcription by RNA polymerase I IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of RNA polymerase I upstream activating factor complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RNA polymerase I upstream activating factor complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of RNA polymerase I upstream activating factor complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Rrn10p
NP_009528.1
  • Protein involved in promoting high level transcription of rDNA; subunit of UAF (upstream activation factor) for RNA polymerase I

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    171481..171918
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178265.1 → NP_009528.1  TPA: Rrn10p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009528.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VPX5, P38204
    UniProtKB/TrEMBL
    A6ZKS3, B3LNG2, C7GX85, C8Z3X1, G2W8Y4, N1P8T2
    Conserved Domains (1) summary
    pfam05234
    Location:1 → 120
    UAF_Rrn10; UAF complex subunit Rrn10
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38204.1

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