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GIP1 protein phosphatase regulator GIP1 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852334, updated on 1-Aug-2024

Summary

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Gene symbol
GIP1
Gene description
protein phosphatase regulator GIP1
Primary source
FungiDB:YBR045C
Locus tag
YBR045C
See related
SGD:S000000249; AllianceGenome:SGD:S000000249; VEuPathDB:YBR045C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables protein phosphatase 1 binding activity and protein phosphatase regulator activity. Involved in ascospore wall assembly and regulation of phosphoprotein phosphatase activity. Located in prospore membrane. Part of protein phosphatase type 1 complex. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See GIP1 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (328173..330092, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Tcm62p Neighboring gene tRNA-Val Neighboring gene NADPH:quinone reductase Neighboring gene Fmp23p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Protein phosphatase type 1-interacting protein Ysw1 is involved in proper septin organization and prospore membrane formation during sporulation. Ishihara M, et al. Eukaryot Cell, 2009 Jul. PMID 19465564, Free PMC Article
  2. A Gip1p-Glc7p phosphatase complex regulates septin organization and spore wall formation. Tachikawa H, et al. J Cell Biol, 2001 Nov 26. PMID 11724821, Free PMC Article
  3. Alternative modes of organellar segregation during sporulation in Saccharomyces cerevisiae. Suda Y, et al. Eukaryot Cell, 2007 Nov. PMID 17905927, Free PMC Article
  4. Arg-Pro-X-Ser/Thr is a consensus phosphoacceptor sequence for the meiosis-specific Ime2 protein kinase in Saccharomyces cerevisiae. Moore M, et al. Biochemistry, 2007 Jan 9. PMID 17198398, Free PMC Article
  5. Dynamic localization of a yeast development-specific PP1 complex during prospore membrane formation is dependent on multiple localization signals and complex formation. Nakamura TS, et al. Mol Biol Cell, 2017 Dec 15. PMID 29046399, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Genetic analysis suggests that a Gip1-Glc7 phosphatase complex regulates prospore membrane extension in parallel to the previously reported Vps13, Spo71, Spo73 pathway.
    Title: Dynamic localization of a yeast development-specific PP1 complex during prospore membrane formation is dependent on multiple localization signals and complex formation.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables protein phosphatase 1 binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables protein phosphatase regulator activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in ascospore wall assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in prospore membrane IDA
Inferred from Direct Assay
more info
 PubMed 
part_of protein phosphatase type 1 complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
protein phosphatase regulator GIP1
NP_009601.2
  • Meiosis-specific regulatory subunit of the Glc7p protein phosphatase; regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    328173..330092 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178393.2 → NP_009601.2  TPA: protein phosphatase regulator GIP1 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009601.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VQ45, P38229
    UniProtKB/TrEMBL
    G2W951, N1P9D2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38229.2

Gene LinkOut

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