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PEX32 Pex32p [ Saccharomyces cerevisiae S288C ]

Gene ID: 852466, updated on 18-Sep-2024

Summary

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Official Symbol
PEX32
Official Full Name
Pex32p
Primary source
SGD:S000000372
Locus tag
YBR168W
See related
AllianceGenome:SGD:S000000372; FungiDB:YBR168W; VEuPathDB:YBR168W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in peroxisome organization. Is integral component of peroxisomal membrane. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See PEX32 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (572371..573612)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene prephenate dehydrogenase (NADP(+)) Neighboring gene ribonuclease P/MRP protein subunit POP7 Neighboring gene adenyl-nucleotide exchange factor SSE2 Neighboring gene nuclear protein localization protein 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pex24 and Pex32 are required to tether peroxisomes to the ER for organelle biogenesis, positioning and segregation in yeast. Wu F, et al. J Cell Sci, 2020 Aug 17. PMID 32665322
  2. Pex19p binds Pex30p and Pex32p at regions required for their peroxisomal localization but separate from their peroxisomal targeting signals. Vizeacoumar FJ, et al. J Biol Chem, 2006 May 26. PMID 16551610
  3. Pex30-like proteins function as adaptors at distinct ER membrane contact sites. Ferreira JV, et al. J Cell Biol, 2021 Oct 4. PMID 34402813, Free PMC Article
  4. Pex30p, Pex31p, and Pex32p form a family of peroxisomal integral membrane proteins regulating peroxisome size and number in Saccharomyces cerevisiae. Vizeacoumar FJ, et al. Mol Biol Cell, 2004 Feb. PMID 14617799, Free PMC Article
  5. Peroxins Pex30 and Pex29 Dynamically Associate with Reticulons to Regulate Peroxisome Biogenesis from the Endoplasmic Reticulum. Mast FD, et al. J Biol Chem, 2016 Jul 22. PMID 27129769, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Pex24 and Pex32 are required to tether peroxisomes to the ER for organelle biogenesis, positioning and segregation in yeast.
    Title: Pex24 and Pex32 are required to tether peroxisomes to the ER for organelle biogenesis, positioning and segregation in yeast.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in peroxisome organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in peroxisome organization IEA
Inferred from Electronic Annotation
more info
  
involved_in peroxisome organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in peroxisomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in peroxisomal membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in peroxisomal membrane IEA
Inferred from Electronic Annotation
more info
  
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Pex32p
NP_009727.3
  • Peroxisomal integral membrane protein; involved in negative regulation of peroxisome size; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    572371..573612
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178516.3 → NP_009727.3  TPA: Pex32p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009727.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VQG4, E9P8W7, P38292
    UniProtKB/TrEMBL
    G2W9H1, N1P6V1
    Conserved Domains (1) summary
    pfam06398
    Location:24 → 408
    Pex24p; Integral peroxisomal membrane peroxin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38292.1

Gene LinkOut

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