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YPT10 Rab family GTPase YPT10 [ Saccharomyces cerevisiae S288C ]

Gene ID: 852567, updated on 18-Sep-2024

Summary

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Official Symbol
YPT10
Official Full Name
Rab family GTPase YPT10
Primary source
SGD:S000000468
Locus tag
YBR264C
See related
AllianceGenome:SGD:S000000468; FungiDB:YBR264C; VEuPathDB:YBR264C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables guanyl nucleotide binding activity. Involved in Golgi organization. Located in fungal-type vacuole membrane. Orthologous to human RAB24 (RAB24, member RAS oncogene family). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See YPT10 in Genome Data Viewer
Location:
chromosome: II
Exon count:
1
Sequence:
Chromosome: II; NC_001134.8 (737770..738369, complement)

Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Mic12p Neighboring gene glycine hydroxymethyltransferase SHM1 Neighboring gene 3-dehydrosphinganine reductase Neighboring gene Rei1p Neighboring gene Slm6p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of the ORF YBR264c in Saccharomyces cerevisiae, which encodes a new yeast Ypt that is degraded by a proteasome-dependent mechanism. Louvet O, et al. Mol Gen Genet, 1999 Jun. PMID 10394895
  2. The complete sequence of a 19,482 bp segment located on the right arm of chromosome II from Saccharomyces cerevisiae. Doignon F, et al. Yeast, 1993 Feb. PMID 8465606
  3. Regulatory sites in the Mon1-Ccz1 complex control Rab5 to Rab7 transition and endosome maturation. Borchers AC, et al. Proc Natl Acad Sci U S A, 2023 Jul 25. PMID 37463208, Free PMC Article
  4. Bioinformatic and comparative localization of Rab proteins reveals functional insights into the uncharacterized GTPases Ypt10p and Ypt11p. Buvelot Frei S, et al. Mol Cell Biol, 2006 Oct. PMID 16980630, Free PMC Article
  5. Saccharomyces cerevisiae Pra1p/Yip3p interacts with Yip1p and Rab proteins. Calero M, et al. Biochem Biophys Res Commun, 2002 Jan 18. PMID 11785952

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables guanyl nucleotide binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in Golgi organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
is_active_in endomembrane system IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in fungal-type vacuole membrane HDA PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in vesicle IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Rab family GTPase YPT10
NP_009823.2
  • Rab family GTP-binding protein; contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001134.8 Reference assembly

    Range
    737770..738369 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001178612.1 → NP_009823.2  TPA: Rab family GTPase YPT10 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_009823.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VQR1, P38146
    UniProtKB/TrEMBL
    A6ZLK4, B3LMP7, C7GMW6, N1PAW3
    Conserved Domains (1) summary
    cd00154
    Location:5 → 158
    Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P38146.2

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